Immune and epithelial determinants of age-related risk and alveolar injury in fatal COVID-19

Respiratory failure in COVID-19 is characterized by widespread disruption of the lung’s alveolar gas exchange interface. To elucidate determinants of alveolar lung damage, we performed epithelial and immune cell profiling in lungs from 24 COVID-19 autopsies and 43 uninfected organ donors ages 18–92...

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Detalles Bibliográficos
Autores principales: Chait, Michael, Yilmaz, Mine M., Shakil, Shanila, Ku, Amy W., Dogra, Pranay, Connors, Thomas J., Szabo, Peter A., Gray, Joshua I., Wells, Steven B., Kubota, Masaru, Matsumoto, Rei, Poon, Maya M.L., Snyder, Mark E., Baldwin, Matthew R., Sims, Peter A., Saqi, Anjali, Farber, Donna L., Weisberg, Stuart P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9228710/
https://www.ncbi.nlm.nih.gov/pubmed/35446789
http://dx.doi.org/10.1172/jci.insight.157608

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