Cargando…

Kinome Analysis to Define Mechanisms of Adjuvant Action: PCEP Induces Unique Signaling at the Injection Site and Lymph Nodes

Understanding the mechanism of action of adjuvants through systems biology enables rationale criteria for their selection, optimization, and application. As kinome analysis has proven valuable for defining responses to infectious agents and providing biomarkers of vaccine responsiveness, it is a log...

Descripción completa

Detalles Bibliográficos
Autores principales:	Awate, Sunita, Scruten, Erin, Mutwiri, George, Napper, Scott
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9228728/ https://www.ncbi.nlm.nih.gov/pubmed/35746541 http://dx.doi.org/10.3390/vaccines10060927

Ejemplares similares

Caspase-1 Dependent IL-1β Secretion and Antigen-Specific T-Cell Activation by the Novel Adjuvant, PCEP
por: Awate, Sunita, et al.
Publicado: (2014)

Mechanisms of Action of Adjuvants
por: Awate, Sunita, et al.
Publicado: (2013)

Peptide Arrays for Kinome Analysis of Livestock Species
por: Daigle, Joanna, et al.
Publicado: (2014)

PIIKA 2.5: Enhanced quality control of peptide microarrays for kinome analysis
por: Denomy, Connor, et al.
Publicado: (2021)

The Adjuvants Polyphosphazene (PCEP) and a Combination of Curdlan Plus Leptin Promote a Th17-Type Immune Response to an Intramuscular Vaccine in Mice
por: Chaffey, Alyssa, et al.
Publicado: (2021)

PCEP enhances IgA mucosal immune responses in mice following different immunization routes with influenza virus antigens
por: Eng, Nelson F, et al.
Publicado: (2010)

Identification of developmentally-specific kinotypes and mechanisms of Varroa mite resistance through whole-organism, kinome analysis of honeybee
por: Robertson, Albert J., et al.
Publicado: (2014)

Experimental PCEP-Adjuvanted Swine Influenza H1N1 Vaccine Induced Strong Immune Responses but Did Not Protect Piglets against Heterologous H3N2 Virus Challenge
por: Magiri, Royford Bundi, et al.
Publicado: (2020)

Vaccine Potentiation by Combination Adjuvants
por: Levast, Benoît, et al.
Publicado: (2014)

Kinome profiling of peripheral blood mononuclear cells collected prior to vaccination reveals biomarkers and potential mechanisms of vaccine unresponsiveness in pigs
por: Lipsit, Sean W. L., et al.
Publicado: (2020)

Kinome Analysis of Honeybee (Apis mellifera L.) Dark-Eyed Pupae Identifies Biomarkers and Mechanisms of Tolerance to Varroa Mite Infestation
por: Robertson, Albert J., et al.
Publicado: (2020)

Non-digestible oligosaccharides directly regulate host kinome to modulate host inflammatory responses without alterations in the gut microbiota
por: Wu, Richard Y., et al.
Publicado: (2017)

Kinome Analysis of Cattle Peripheral Lymph Nodes to Elucidate Differential Response to Salmonella spp.
por: Arsenault, Ryan J., et al.
Publicado: (2022)

Vaccine Formulation for Infectious Diseases and Adjuvant Mechanisms of Action
por: Wilson, Heather L., et al.
Publicado: (2021)

Validation of the German revised version of the program in palliative care education and practice questionnaire (PCEP-GR)
por: Fetz, Katharina, et al.
Publicado: (2017)

PIIKA 2: An Expanded, Web-Based Platform for Analysis of Kinome Microarray Data
por: Trost, Brett, et al.
Publicado: (2013)

Plasma Cytokines and Birth Weight as Biomarkers of Vaccine-Induced Humoral Responses in Piglets
por: Lipsit, Sean, et al.
Publicado: (2022)

Correction: PIIKA 2: An Expanded, Web-Based Platform for Analysis of Kinome Microarray Data
por: Trost, Brett, et al.
Publicado: (2014)

Kinotypes: stable species- and individual-specific profiles of cellular kinase activity
por: Trost, Brett, et al.
Publicado: (2013)

Kinome Profiling
por: Peppelenbosch, Maikel P.
Publicado: (2012)

Signaling differences in peripheral blood mononuclear cells of high and low vaccine responders prior to, and following, vaccination in piglets
por: Lipsit, Sean, et al.
Publicado: (2022)

Perforated Concave Earplug (pCEP): A Proof-of-Concept Earplug to Improve Sound Localization without Compromising Noise Attenuation
por: Fink, Nir, et al.
Publicado: (2023)

From Beef to Bees: High-Throughput Kinome Analysis to Understand Host Responses of Livestock Species to Infectious Diseases and Industry-Associated Stress
por: Facciuolo, Antonio, et al.
Publicado: (2020)

The minimal kinome of Giardia lamblia illuminates early kinase evolution and unique parasite biology
por: Manning, Gerard, et al.
Publicado: (2011)

Kinome profiling of BLV-induced ovine leukemia: an approach for identifying altered signaling pathways associated with oncogenesis
por: Van den Broeke, Anne, et al.
Publicado: (2011)

PASSIVE TRANSFER OF ADJUVANT ARTHRITIS BY LYMPH NODE OR SPLEEN CELLS
por: Pearson, Carl M., et al.
Publicado: (1964)

Adjuvant radiation therapy in metastatic lymph nodes from melanoma
por: Bibault, Jean-Emmanuel, et al.
Publicado: (2011)

The Cryptosporidium parvum Kinome
por: Artz, Jennifer D, et al.
Publicado: (2011)

Intra-lymph Node Injection of Biodegradable Polymer Particles
por: Andorko, James I., et al.
Publicado: (2014)

Induction of PrP(Sc)-specific systemic and mucosal immune responses in white-tailed deer with an oral vaccine for chronic wasting disease
por: Taschuk, Ryan, et al.
Publicado: (2017)

Defining the Schistosoma haematobium kinome enables the prediction of essential kinases as anti-schistosome drug targets
por: Stroehlein, Andreas J., et al.
Publicado: (2015)

Lymph Node Number Predicts the Efficacy of Adjuvant Chemoradiotherapy in Node-Positive Endometrial Cancer Patients
por: Lee, Jie, et al.
Publicado: (2020)

Biodegradable Polymeric Nanoparticles-Based Vaccine Adjuvants for Lymph Nodes Targeting
por: Gutjahr, Alice, et al.
Publicado: (2016)

Adjuvant Treatment Approaches after Radical Prostatectomy with Lymph Node Involvement
por: Tavukçu, Hasan Hüseyin, et al.
Publicado: (2022)

Kinomics toolbox—A web platform for analysis and viewing of kinomic peptide array data
por: Dussaq, Alex M., et al.
Publicado: (2018)

Defining the role of lymph node metastasis in systemic breast cancer evolution
por: Naxerova, Kamila
Publicado: (2020)

Significance of examined lymph nodes number and metastatic lymph nodes ratio in overall survival and adjuvant treatment decision in resected laryngeal carcinoma
por: Zhu, Xiaoke, et al.
Publicado: (2020)

Outcomes with adjuvant anti-PD-1 therapy in patients with sentinel lymph node-positive melanoma without completion lymph node dissection
por: Eroglu, Zeynep, et al.
Publicado: (2022)

Oncologic Benefit of Adjuvant Therapy in Lateral Pelvic Lymph Node Metastasis following Neoadjuvant Chemoradiotherapy and Lateral Pelvic Lymph Node Dissection
por: Jiang, Yu-Juan, et al.
Publicado: (2022)

Comparative kinomics of human and chimpanzee reveal unique kinship and functional diversity generated by new domain combinations
por: Anamika, Krishanpal, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_jpoc25cdk009863c5cq8rcrhba