Novel Radioiodinated and Radiofluorinated Analogues of FT-2102 for SPECT or PET Imaging of mIDH1 Mutant Tumours

Isocitrate dehydrogenases (IDHs) are metabolic enzymes commonly mutated in human cancers (glioma, acute myeloid leukaemia, chondrosarcoma, and intrahepatic cholangiocarcinoma). These mutated variants of IDH (mIDH) acquire a neomorphic activity, namely, conversion of α-ketoglutarate to the oncometabo...

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Detalles Bibliográficos
Autores principales: Weber, Valérie, Arnaud, Lucie, Dukic-Stefanovic, Sladjana, Wenzel, Barbara, Roux, Valérie, Chezal, Jean-Michel, Lai, Thu-Hang, Teodoro, Rodrigo, Kopka, Klaus, Miot-Noirault, Elisabeth, Deuther-Conrad, Winnie, Maisonial-Besset, Aurélie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9228733/
https://www.ncbi.nlm.nih.gov/pubmed/35744895
http://dx.doi.org/10.3390/molecules27123766

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9228733/
https://www.ncbi.nlm.nih.gov/pubmed/35744895
http://dx.doi.org/10.3390/molecules27123766

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