Enalapril and Enalaprilat Pharmacokinetics in Children with Heart Failure Due to Dilated Cardiomyopathy and Congestive Heart Failure after Administration of an Orodispersible Enalapril Minitablet (LENA-Studies)

Angiotensin-converting enzyme inhibitors (ACEI), such as enalapril, are a cornerstone of treatment for pediatric heart failure which is still used off-label. Using a novel age-appropriate formulation of enalapril orodispersible minitablets (ODMTs), phase II/III open-label, multicenter pharmacokineti...

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Detalles Bibliográficos
Autores principales: Laeer, Stephanie, Cawello, Willi, Burckhardt, Bjoern B., Ablonczy, László, Bajcetic, Milica, Breur, Johannes M. P. J., Dalinghaus, Michiel, Male, Christoph, de Wildt, Saskia N., Breitkreutz, Jörg, Faisal, Muhammed, Keatley-Clarke, Anne, Klingmann, Ingrid, Lagler, Florian B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9228797/
https://www.ncbi.nlm.nih.gov/pubmed/35745735
http://dx.doi.org/10.3390/pharmaceutics14061163

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