Cargando…

Shotgun Proteomics Revealed Preferential Degradation of Misfolded In Vivo Obligate GroE Substrates by Lon Protease in Escherichia coli

The Escherichia coli chaperonin GroEL/ES (GroE) is one of the most extensively studied molecular chaperones. So far, ~80 proteins in E. coli are identified as GroE substrates that obligately require GroE for folding in vivo. In GroE-depleted cells, these substrates, when overexpressed, tend to form...

Descripción completa

Detalles Bibliográficos
Autores principales: Niwa, Tatsuya, Chadani, Yuhei, Taguchi, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9228906/
https://www.ncbi.nlm.nih.gov/pubmed/35744894
http://dx.doi.org/10.3390/molecules27123772

Ejemplares similares