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Synthesis, Physicochemical, Labeling and In Vivo Characterization of (44)Sc-Labeled DO3AM-NI as a Hypoxia-Sensitive PET Probe

Hypoxia promotes angiogenesis, which is crucial for tumor growth, and induces malignant progression and increases the therapeutic resistance. Positron emission tomography (PET) enables the detection of the hypoxic regions in tumors using 2-nitroimidazole-based radiopharmaceuticals. We describe here...

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Detalles Bibliográficos
Autores principales:	Szücs, Dániel, Csupász, Tibor, Szabó, Judit P., Kis, Adrienn, Gyuricza, Barbara, Arató, Viktória, Forgács, Viktória, Vágner, Adrienn, Nagy, Gábor, Garai, Ildikó, Szikra, Dezső, Tóth, Imre, Trencsényi, György, Tircsó, Gyula, Fekete, Anikó
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9228955/ https://www.ncbi.nlm.nih.gov/pubmed/35745585 http://dx.doi.org/10.3390/ph15060666

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