Recent Progress in the Synthesis of Drugs and Bioactive Molecules Incorporating Nitro(het)arene Core

Aromatic nitro compounds play a unique role in the synthesis of drugs and pharmaceutically oriented molecules. This field of organic chemistry continues to be in demand and relevant. A significant number of papers are published annually on new general methods for the synthesis of nitrodrugs and rela...

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Detalles Bibliográficos
Autores principales: Bastrakov, Maxim, Starosotnikov, Alexey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9228974/
https://www.ncbi.nlm.nih.gov/pubmed/35745627
http://dx.doi.org/10.3390/ph15060705
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author Bastrakov, Maxim
Starosotnikov, Alexey
author_facet Bastrakov, Maxim
Starosotnikov, Alexey
author_sort Bastrakov, Maxim
collection PubMed
description Aromatic nitro compounds play a unique role in the synthesis of drugs and pharmaceutically oriented molecules. This field of organic chemistry continues to be in demand and relevant. A significant number of papers are published annually on new general methods for the synthesis of nitrodrugs and related biomolecules. This review is an analysis of the literature on methods for the synthesis of both new and already-known aromatic and heteroaromatic nitrodrugs covering the period from 2010 to the present.
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spelling pubmed-92289742022-06-25 Recent Progress in the Synthesis of Drugs and Bioactive Molecules Incorporating Nitro(het)arene Core Bastrakov, Maxim Starosotnikov, Alexey Pharmaceuticals (Basel) Review Aromatic nitro compounds play a unique role in the synthesis of drugs and pharmaceutically oriented molecules. This field of organic chemistry continues to be in demand and relevant. A significant number of papers are published annually on new general methods for the synthesis of nitrodrugs and related biomolecules. This review is an analysis of the literature on methods for the synthesis of both new and already-known aromatic and heteroaromatic nitrodrugs covering the period from 2010 to the present. MDPI 2022-06-03 /pmc/articles/PMC9228974/ /pubmed/35745627 http://dx.doi.org/10.3390/ph15060705 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Bastrakov, Maxim
Starosotnikov, Alexey
Recent Progress in the Synthesis of Drugs and Bioactive Molecules Incorporating Nitro(het)arene Core
title Recent Progress in the Synthesis of Drugs and Bioactive Molecules Incorporating Nitro(het)arene Core
title_full Recent Progress in the Synthesis of Drugs and Bioactive Molecules Incorporating Nitro(het)arene Core
title_fullStr Recent Progress in the Synthesis of Drugs and Bioactive Molecules Incorporating Nitro(het)arene Core
title_full_unstemmed Recent Progress in the Synthesis of Drugs and Bioactive Molecules Incorporating Nitro(het)arene Core
title_short Recent Progress in the Synthesis of Drugs and Bioactive Molecules Incorporating Nitro(het)arene Core
title_sort recent progress in the synthesis of drugs and bioactive molecules incorporating nitro(het)arene core
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9228974/
https://www.ncbi.nlm.nih.gov/pubmed/35745627
http://dx.doi.org/10.3390/ph15060705
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