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Bovine Pancreatic RNase A: An Insight into the Mechanism of Antitumor Activity In Vitro and In Vivo

In this investigation, we extensively studied the mechanism of antitumor activity of bovine pancreatic RNase A. Using confocal microscopy, we show that after RNase A penetration into HeLa and B16 cells, a part of the enzyme remains unbound with the ribonuclease inhibitor (RI), resulting in the decre...

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Detalles Bibliográficos
Autores principales:	Mohamed, Islam Saber Ead, Sen’kova, Aleksandra V., Markov, Oleg V., Markov, Andrey V., Savin, Innokenty A., Zenkova, Marina A., Mironova, Nadezhda L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9229056/ https://www.ncbi.nlm.nih.gov/pubmed/35745743 http://dx.doi.org/10.3390/pharmaceutics14061173

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