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Design of a US28 ORF Deletion Virus in a Temperature-Sensitive Cytomegalovirus Strain Fails to Promote Lytic Replication in Hematopoietic Cells

Human cytomegalovirus (CMV) is a ubiquitous pathogen that latently resides in hematopoietic cells. Latently infected individuals with dysfunctional immune systems often experience CMV reactivation, which can cause devastating disease and mortality. While factors dictating the balance between latency...

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Detalles Bibliográficos
Autores principales: Krishna, Benjamin A., Wass, Amanda B., Murphy, Eain A., O’Connor, Christine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9229150/
https://www.ncbi.nlm.nih.gov/pubmed/35746751
http://dx.doi.org/10.3390/v14061280

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