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SARS-CoV-2 Infection in Companion Animals: Prospective Serological Survey and Risk Factor Analysis in France

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), responsible for COVID-19 in people, has been detected in companion animals on rare occasions. A limited number of large-scale studies have investigated the exposure of companion animals to SARS-CoV-2. The objective of this prospective stu...

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Autores principales: Bessière, Pierre, Vergne, Timothée, Battini, Matéo, Brun, Jessie, Averso, Julien, Joly, Etienne, Guérin, Jean-Luc, Cadiergues, Marie-Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9229200/
https://www.ncbi.nlm.nih.gov/pubmed/35746652
http://dx.doi.org/10.3390/v14061178
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author Bessière, Pierre
Vergne, Timothée
Battini, Matéo
Brun, Jessie
Averso, Julien
Joly, Etienne
Guérin, Jean-Luc
Cadiergues, Marie-Christine
author_facet Bessière, Pierre
Vergne, Timothée
Battini, Matéo
Brun, Jessie
Averso, Julien
Joly, Etienne
Guérin, Jean-Luc
Cadiergues, Marie-Christine
author_sort Bessière, Pierre
collection PubMed
description Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), responsible for COVID-19 in people, has been detected in companion animals on rare occasions. A limited number of large-scale studies have investigated the exposure of companion animals to SARS-CoV-2. The objective of this prospective study was to estimate seroprevalence in privately owned dogs and cats presented in veterinary clinics in different French regions and to test the hypothesis that the occurrence of an episode of COVID-19 in the household and close contact with the owner would increase the chances of the animals being seropositive. One hundred and sixty-five dogs and 143 cats were blood-sampled between March 2020 and December 2021. Neutralizing SARS-CoV-2 antibodies were detected in 8.4% of cats (12/143) and 5.4% of dogs (9/165). Seven animals (three dogs and four cats) were seropositive in the absence of an episode of COVID-19 in the household. Despite not being statistically significant (chi-square test, p-value = 0.55), our data may suggest that the occurrence of an episode of COVID-19 in the household could increase the risk of animal seropositivity (odds ratio = 1.38; 95% confidence interval = 0.55–3.77). This survey indirectly shows that SARS-CoV-2 circulates in canine and feline populations, but its circulation appears to be too low for pets to act as a significant viral reservoir.
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spelling pubmed-92292002022-06-25 SARS-CoV-2 Infection in Companion Animals: Prospective Serological Survey and Risk Factor Analysis in France Bessière, Pierre Vergne, Timothée Battini, Matéo Brun, Jessie Averso, Julien Joly, Etienne Guérin, Jean-Luc Cadiergues, Marie-Christine Viruses Communication Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), responsible for COVID-19 in people, has been detected in companion animals on rare occasions. A limited number of large-scale studies have investigated the exposure of companion animals to SARS-CoV-2. The objective of this prospective study was to estimate seroprevalence in privately owned dogs and cats presented in veterinary clinics in different French regions and to test the hypothesis that the occurrence of an episode of COVID-19 in the household and close contact with the owner would increase the chances of the animals being seropositive. One hundred and sixty-five dogs and 143 cats were blood-sampled between March 2020 and December 2021. Neutralizing SARS-CoV-2 antibodies were detected in 8.4% of cats (12/143) and 5.4% of dogs (9/165). Seven animals (three dogs and four cats) were seropositive in the absence of an episode of COVID-19 in the household. Despite not being statistically significant (chi-square test, p-value = 0.55), our data may suggest that the occurrence of an episode of COVID-19 in the household could increase the risk of animal seropositivity (odds ratio = 1.38; 95% confidence interval = 0.55–3.77). This survey indirectly shows that SARS-CoV-2 circulates in canine and feline populations, but its circulation appears to be too low for pets to act as a significant viral reservoir. MDPI 2022-05-28 /pmc/articles/PMC9229200/ /pubmed/35746652 http://dx.doi.org/10.3390/v14061178 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Communication
Bessière, Pierre
Vergne, Timothée
Battini, Matéo
Brun, Jessie
Averso, Julien
Joly, Etienne
Guérin, Jean-Luc
Cadiergues, Marie-Christine
SARS-CoV-2 Infection in Companion Animals: Prospective Serological Survey and Risk Factor Analysis in France
title SARS-CoV-2 Infection in Companion Animals: Prospective Serological Survey and Risk Factor Analysis in France
title_full SARS-CoV-2 Infection in Companion Animals: Prospective Serological Survey and Risk Factor Analysis in France
title_fullStr SARS-CoV-2 Infection in Companion Animals: Prospective Serological Survey and Risk Factor Analysis in France
title_full_unstemmed SARS-CoV-2 Infection in Companion Animals: Prospective Serological Survey and Risk Factor Analysis in France
title_short SARS-CoV-2 Infection in Companion Animals: Prospective Serological Survey and Risk Factor Analysis in France
title_sort sars-cov-2 infection in companion animals: prospective serological survey and risk factor analysis in france
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9229200/
https://www.ncbi.nlm.nih.gov/pubmed/35746652
http://dx.doi.org/10.3390/v14061178
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