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Cu(2+)-Chelating Mesoporous Silica Nanoparticles for Synergistic Chemotherapy/Chemodynamic Therapy

In this study, a pH-responsive controlled-release mesoporous silica nanoparticle (MSN) formulation was developed. The MSNs were functionalized with a histidine (His)-tagged targeting peptide (B3int) through an amide bond, and loaded with an anticancer drug (cisplatin (CP)) and a lysosomal destabiliz...

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Detalles Bibliográficos
Autores principales: Zhang, Yanyan, Lou, Jiadong, Williams, Gareth R., Ye, Yuhan, Ren, Dandan, Shi, Anhua, Wu, Junzi, Chen, Wenling, Zhu, Li-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9229203/
https://www.ncbi.nlm.nih.gov/pubmed/35745773
http://dx.doi.org/10.3390/pharmaceutics14061200