Navitoclax Enhances the Therapeutic Effects of PLK1 Targeting on Lung Cancer Cells in 2D and 3D Culture Systems

The efficacy of antimitotics is limited by slippage, whereby treated cells arrested in mitosis exit mitosis without cell division and, eventually, escape apoptosis, constituting a serious resistance mechanism to antimitotics. Strategies to overcome slippage should potentiate the cancer cell killing...

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Detalles Bibliográficos
Autores principales: Pinto, Bárbara, Novais, Pedro, Henriques, Ana C., Carvalho-Tavares, Juliana, Silva, Patrícia M. A., Bousbaa, Hassan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9229367/
https://www.ncbi.nlm.nih.gov/pubmed/35745782
http://dx.doi.org/10.3390/pharmaceutics14061209

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9229367/
https://www.ncbi.nlm.nih.gov/pubmed/35745782
http://dx.doi.org/10.3390/pharmaceutics14061209

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