Cargando…
Facile Synthesized Cu–RGO and Ag–RGO Nanocomposites with Potential Biomedical Applications
In the present study, we report on the facile prepared nanocomposites of reduced graphene oxide RGO with Cu and Ag. The synthesis was performed through an environmentally friendly and easy method by simultaneous reduction in solutions containing Cu(2+) or Ag(+) and graphene oxide (GO) using zinc pow...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9229401/ https://www.ncbi.nlm.nih.gov/pubmed/35745432 http://dx.doi.org/10.3390/nano12122096 |
_version_ | 1784734738190172160 |
---|---|
author | Kichukova, Diana Spassova, Ivanka Kostadinova, Aneliya Staneva, Anna Kovacheva, Daniela |
author_facet | Kichukova, Diana Spassova, Ivanka Kostadinova, Aneliya Staneva, Anna Kovacheva, Daniela |
author_sort | Kichukova, Diana |
collection | PubMed |
description | In the present study, we report on the facile prepared nanocomposites of reduced graphene oxide RGO with Cu and Ag. The synthesis was performed through an environmentally friendly and easy method by simultaneous reduction in solutions containing Cu(2+) or Ag(+) and graphene oxide (GO) using zinc powder as a reducing agent in aqueous acidic media. The composites are characterized by powder X-ray diffraction, low-temperature nitrogen adsorption, X-ray photoelectron and FTIR and Raman spectroscopies, as well as Scanning and Transmission electron microscopies. The antibacterial activity of the composites was tested for Staphylococcus aureus, Escherichia coli and antifungal activity for Candida albicans. The cytotoxicity of the materials was studied towards two types of eukaryotic cells—MDCK II and A549 cell lines. The composites obtained consist of homogeneously distributed Cu and Ag nanoparticles on the surface of graphene sheets and manifest good antimicrobial activity and high cytotoxicity. The results clearly show that both metal–RGO composites can be successfully used as antimicrobial and anticancer agents. |
format | Online Article Text |
id | pubmed-9229401 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-92294012022-06-25 Facile Synthesized Cu–RGO and Ag–RGO Nanocomposites with Potential Biomedical Applications Kichukova, Diana Spassova, Ivanka Kostadinova, Aneliya Staneva, Anna Kovacheva, Daniela Nanomaterials (Basel) Article In the present study, we report on the facile prepared nanocomposites of reduced graphene oxide RGO with Cu and Ag. The synthesis was performed through an environmentally friendly and easy method by simultaneous reduction in solutions containing Cu(2+) or Ag(+) and graphene oxide (GO) using zinc powder as a reducing agent in aqueous acidic media. The composites are characterized by powder X-ray diffraction, low-temperature nitrogen adsorption, X-ray photoelectron and FTIR and Raman spectroscopies, as well as Scanning and Transmission electron microscopies. The antibacterial activity of the composites was tested for Staphylococcus aureus, Escherichia coli and antifungal activity for Candida albicans. The cytotoxicity of the materials was studied towards two types of eukaryotic cells—MDCK II and A549 cell lines. The composites obtained consist of homogeneously distributed Cu and Ag nanoparticles on the surface of graphene sheets and manifest good antimicrobial activity and high cytotoxicity. The results clearly show that both metal–RGO composites can be successfully used as antimicrobial and anticancer agents. MDPI 2022-06-17 /pmc/articles/PMC9229401/ /pubmed/35745432 http://dx.doi.org/10.3390/nano12122096 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Kichukova, Diana Spassova, Ivanka Kostadinova, Aneliya Staneva, Anna Kovacheva, Daniela Facile Synthesized Cu–RGO and Ag–RGO Nanocomposites with Potential Biomedical Applications |
title | Facile Synthesized Cu–RGO and Ag–RGO Nanocomposites with Potential Biomedical Applications |
title_full | Facile Synthesized Cu–RGO and Ag–RGO Nanocomposites with Potential Biomedical Applications |
title_fullStr | Facile Synthesized Cu–RGO and Ag–RGO Nanocomposites with Potential Biomedical Applications |
title_full_unstemmed | Facile Synthesized Cu–RGO and Ag–RGO Nanocomposites with Potential Biomedical Applications |
title_short | Facile Synthesized Cu–RGO and Ag–RGO Nanocomposites with Potential Biomedical Applications |
title_sort | facile synthesized cu–rgo and ag–rgo nanocomposites with potential biomedical applications |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9229401/ https://www.ncbi.nlm.nih.gov/pubmed/35745432 http://dx.doi.org/10.3390/nano12122096 |
work_keys_str_mv | AT kichukovadiana facilesynthesizedcurgoandagrgonanocompositeswithpotentialbiomedicalapplications AT spassovaivanka facilesynthesizedcurgoandagrgonanocompositeswithpotentialbiomedicalapplications AT kostadinovaaneliya facilesynthesizedcurgoandagrgonanocompositeswithpotentialbiomedicalapplications AT stanevaanna facilesynthesizedcurgoandagrgonanocompositeswithpotentialbiomedicalapplications AT kovachevadaniela facilesynthesizedcurgoandagrgonanocompositeswithpotentialbiomedicalapplications |