Sudden Onset of IgA Vasculitis Affecting Vital Organs in Adult Patients following SARS-CoV-2 Vaccines

IgA vasculitis is an immune complex-mediated small-vessel vasculitis that mainly occurs in children and is characterized by palpable purpura, arthralgia, abdominal pain, and glomerulonephritis. We report three cases of new-onset IgA vasculitis involving major organs in adult patients after they rece...

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Autores principales: Choi, Yunjung, Lee, Chang Hun, Kim, Kyoung Min, Yoo, Wan-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9229537/
https://www.ncbi.nlm.nih.gov/pubmed/35746531
http://dx.doi.org/10.3390/vaccines10060923
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author Choi, Yunjung
Lee, Chang Hun
Kim, Kyoung Min
Yoo, Wan-Hee
author_facet Choi, Yunjung
Lee, Chang Hun
Kim, Kyoung Min
Yoo, Wan-Hee
author_sort Choi, Yunjung
collection PubMed
description IgA vasculitis is an immune complex-mediated small-vessel vasculitis that mainly occurs in children and is characterized by palpable purpura, arthralgia, abdominal pain, and glomerulonephritis. We report three cases of new-onset IgA vasculitis involving major organs in adult patients after they received either the ChAdOx1 viral vector (Oxford/AstraZeneca) vaccine or the messenger RNA-1273 (Moderna) vaccine. These cases suggest that COVID-19 vaccines have the potential to trigger IgA vasculitis and indicate that physicians need to monitor for this possible complication.
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spelling pubmed-92295372022-06-25 Sudden Onset of IgA Vasculitis Affecting Vital Organs in Adult Patients following SARS-CoV-2 Vaccines Choi, Yunjung Lee, Chang Hun Kim, Kyoung Min Yoo, Wan-Hee Vaccines (Basel) Case Report IgA vasculitis is an immune complex-mediated small-vessel vasculitis that mainly occurs in children and is characterized by palpable purpura, arthralgia, abdominal pain, and glomerulonephritis. We report three cases of new-onset IgA vasculitis involving major organs in adult patients after they received either the ChAdOx1 viral vector (Oxford/AstraZeneca) vaccine or the messenger RNA-1273 (Moderna) vaccine. These cases suggest that COVID-19 vaccines have the potential to trigger IgA vasculitis and indicate that physicians need to monitor for this possible complication. MDPI 2022-06-09 /pmc/articles/PMC9229537/ /pubmed/35746531 http://dx.doi.org/10.3390/vaccines10060923 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Choi, Yunjung
Lee, Chang Hun
Kim, Kyoung Min
Yoo, Wan-Hee
Sudden Onset of IgA Vasculitis Affecting Vital Organs in Adult Patients following SARS-CoV-2 Vaccines
title Sudden Onset of IgA Vasculitis Affecting Vital Organs in Adult Patients following SARS-CoV-2 Vaccines
title_full Sudden Onset of IgA Vasculitis Affecting Vital Organs in Adult Patients following SARS-CoV-2 Vaccines
title_fullStr Sudden Onset of IgA Vasculitis Affecting Vital Organs in Adult Patients following SARS-CoV-2 Vaccines
title_full_unstemmed Sudden Onset of IgA Vasculitis Affecting Vital Organs in Adult Patients following SARS-CoV-2 Vaccines
title_short Sudden Onset of IgA Vasculitis Affecting Vital Organs in Adult Patients following SARS-CoV-2 Vaccines
title_sort sudden onset of iga vasculitis affecting vital organs in adult patients following sars-cov-2 vaccines
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9229537/
https://www.ncbi.nlm.nih.gov/pubmed/35746531
http://dx.doi.org/10.3390/vaccines10060923
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