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Therapeutic Drug Monitoring of Tacrolimus-Personalized Therapy in Heart Transplantation: New Strategies and Preliminary Results in Endomyocardial Biopsies
Tacrolimus (TAC) is an immunosuppressant drug approved both in the US and in the EU, widely used for the prophylaxis of organ rejection after transplantation. This is a critical dose drug: low levels in whole blood can lead to low exposure and a high risk of acute rejection, whereas overexposure put...
Autores principales: | De Gregori, Simona, De Silvestri, Annalisa, Cattadori, Barbara, Rapagnani, Andrea, Albertini, Riccardo, Novello, Elisa, Concardi, Monica, Arbustini, Eloisa, Pellegrini, Carlo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9229567/ https://www.ncbi.nlm.nih.gov/pubmed/35745819 http://dx.doi.org/10.3390/pharmaceutics14061247 |
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