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A Hemagglutinin Stem Vaccine Designed Rationally by AlphaFold2 Confers Broad Protection against Influenza B Infection

Two lineages of influenza B viruses (IBV) co-circulating in human beings have been posing a significant public health burden worldwide. A substantial number of broadly neutralizing antibodies (bnAbs) have been identified targeting conserved epitopes on hemagglutinin (HA) stem domain, posing great in...

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Detalles Bibliográficos
Autores principales: Zeng, Dian, Xin, Jiabao, Yang, Kunyu, Guo, Shuxin, Wang, Qian, Gao, Ying, Chen, Huiqing, Ge, Jiaqi, Lu, Zhen, Zhang, Limin, Chen, Junyu, Chen, Yixin, Xia, Ningshao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9229588/
https://www.ncbi.nlm.nih.gov/pubmed/35746776
http://dx.doi.org/10.3390/v14061305