ORFeome Phage Display Reveals a Major Immunogenic Epitope on the S2 Subdomain of SARS-CoV-2 Spike Protein

The development of antibody therapies against SARS-CoV-2 remains a challenging task during the ongoing COVID-19 pandemic. All approved therapeutic antibodies are directed against the receptor binding domain (RBD) of the spike, and therefore lose neutralization efficacy against emerging SARS-CoV-2 va...

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Detalles Bibliográficos
Autores principales: Ballmann, Rico, Hotop, Sven-Kevin, Bertoglio, Federico, Steinke, Stephan, Heine, Philip Alexander, Chaudhry, M. Zeeshan, Jahn, Dieter, Pucker, Boas, Baldanti, Fausto, Piralla, Antonio, Schubert, Maren, Čičin-Šain, Luka, Brönstrup, Mark, Hust, Michael, Dübel, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9229677/
https://www.ncbi.nlm.nih.gov/pubmed/35746797
http://dx.doi.org/10.3390/v14061326

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9229677/
https://www.ncbi.nlm.nih.gov/pubmed/35746797
http://dx.doi.org/10.3390/v14061326

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