Cargando…

Nobiletin as a Neuroprotectant against NMDA Receptors: An In Silico Approach

Excitotoxicity is a type of neurodegenerative disorder. It caused by excessive glutamate receptor activation, which leads to neuronal malfunction and fatality. The N-methyl-D-aspartate (NMDA) receptors are found in glutamatergic neurons, and their excessive activation is primarily responsible for ex...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jahan, Sadaf, Redhu, Neeru Singh, Siddiqui, Arif Jamal, Iqbal, Danish, Khan, Johra, Banawas, Saeed, Alaidarous, Mohammed, Alshehri, Bader, Mir, Shabir Ahmad, Adnan, Mohd, Pant, Aditya Bhushan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9229780/ https://www.ncbi.nlm.nih.gov/pubmed/35745697 http://dx.doi.org/10.3390/pharmaceutics14061123

Ejemplares similares

Nobiletin Ameliorates Cellular Damage and Stress Response and Restores Neuronal Identity Altered by Sodium Arsenate Exposure in Human iPSCs-Derived hNPCs
por: Jahan, Sadaf, et al.
Publicado: (2022)

Neurological Manifestation of SARS-CoV-2 Induced Inflammation and Possible Therapeutic Strategies Against COVID-19
por: Kumar, Dipak, et al.
Publicado: (2021)

Pioneer Role of Extracellular Vesicles as Modulators of Cancer Initiation in Progression, Drug Therapy, and Vaccine Prospects
por: Jahan, Sadaf, et al.
Publicado: (2022)

Targeting NMDA receptor in Alzheimer’s disease: identifying novel inhibitors using computational approaches
por: Siddiqui, Arif Jamal, et al.
Publicado: (2023)

Prevalence of rheumatoid arthritis and diagnostic validity of a prediction score, in patients visiting orthropedic clinics in the Madinah region of Saudi Arabia: a retrospective cross-sectional study
por: Mir, Shabir Ahmad, et al.
Publicado: (2022)

Immunoinformatics-Based Identification of B and T Cell Epitopes in RNA-Dependent RNA Polymerase of SARS-CoV-2
por: Mir, Shabir Ahmad, et al.
Publicado: (2022)

Seroprevalence of Viral Hepatitis B and C among Blood Donors in the Northern Region of Riyadh Province, Saudi Arabia
por: Alqahtani, Saeed Mohammed, et al.
Publicado: (2021)

Identification of SARS-CoV-2 RNA-dependent RNA polymerase inhibitors from the major phytochemicals of Nigella sativa: An in silico approach
por: Mir, Shabir Ahmad, et al.
Publicado: (2022)

Multidrug-Resistant Bacteria Associated with Cell Phones of Healthcare Professionals in Selected Hospitals in Saudi Arabia
por: Banawas, Saeed, et al.
Publicado: (2018)

Neuroprotection: Targeting Multiple Pathways by Naturally Occurring Phytochemicals
por: Khan, Andleeb, et al.
Publicado: (2020)

Predictive Modeling and Validation on Growth, Production of Asexual Spores and Ochratoxin A of Aspergillus Ochraceus Group under Abiotic Climatic Variables
por: Abdel-Hadi, Ahmed, et al.
Publicado: (2021)

Perspective Insights to Bio-Nanomaterials for the Treatment of Neurological Disorders
por: Khan, Johra, et al.
Publicado: (2021)

Myco-Synthesis of Silver Nanoparticles and Their Bioactive Role against Pathogenic Microbes
por: Abdel-Hadi, Ahmed, et al.
Publicado: (2023)

Nobiletin Exhibits Neuroprotective Effects against Mitochondrial Complex I Inhibition via Regulating Apoptotic Signaling
por: Amarsanaa, Khulan, et al.
Publicado: (2021)

Neuroprotective effects of nobiletin on cerebral ischemia/reperfusion injury rats by inhibiting Rho/ROCK signaling pathway
por: Huang, Dan, et al.
Publicado: (2022)

Exploring the Binding Pattern of Geraniol with Acetylcholinesterase through In Silico Docking, Molecular Dynamics Simulation, and In Vitro Enzyme Inhibition Kinetics Studies
por: Iqbal, Danish, et al.
Publicado: (2021)

Seroprevalence of hepatitis B and C viral infections in the premarital adult population of Al Majmaah, Saudi Arabia
por: Mir, Shabir Ahmad, et al.
Publicado: (2021)

Therapeutic potential of nitric oxide synthase inhibitor from natural sources for the treatment of ischemic stroke
por: Alshehri, Bader, et al.
Publicado: (2022)

Effect of Nobiletin on Experimental Model of Epilepsy
por: Yang, Baowang, et al.
Publicado: (2018)

A Critical Review on Human Malaria and Schistosomiasis Vaccines: Current State, Recent Advancements, and Developments
por: Siddiqui, Arif Jamal, et al.
Publicado: (2023)

Repurposing of phytomedicine-derived bioactive compounds with promising anti-SARS-CoV-2 potential: Molecular docking, MD simulation and drug-likeness/ADMET studies
por: Rudrapal, Mithun, et al.
Publicado: (2022)

Antileishmanial Evaluation of Bark Methanolic Extract of Acacia nilotica: In Vitro and In Silico Studies
por: Ali, Rahat, et al.
Publicado: (2021)

Assessment of the Antileishmanial Potential of Cassia fistula Leaf Extract
por: Tabrez, Shams, et al.
Publicado: (2021)

Whole-Exome Sequencing Reveals Migraine-Associated Novel Functional Variants in Arab Ancestry Females: A Pilot Study
por: Khan, Johra, et al.
Publicado: (2022)

Pharmacological actions of nobiletin in the modulation of platelet function
por: Vaiyapuri, Sakthivel, et al.
Publicado: (2015)

Transdermal delivery of nobiletin using ionic liquids
por: Hattori, Tadashi, et al.
Publicado: (2019)

Targeting NMDA receptors in stroke: new hope in neuroprotection
por: Wu, Qiu Jing, et al.
Publicado: (2018)

The Neuroprotective Effects of SIRT1 on NMDA-Induced Excitotoxicity
por: Yang, Xiaorong, et al.
Publicado: (2017)

Targeting NMDA Receptors in Emotional Disorders: Their Role in Neuroprotection
por: Wang, Siqi, et al.
Publicado: (2022)

Anti-quorum Sensing and Anti-biofilm Activity of Zinc Oxide Nanospikes
por: Khan, Mohd. Farhan, et al.
Publicado: (2020)

Mucormycosis: A hidden mystery of fungal infection, possible diagnosis, treatment and development of new therapeutic agents
por: Hussain, Mohd Kamil, et al.
Publicado: (2023)

The Multifunctional Effects of Nobiletin and Its Metabolites In Vivo and In Vitro
por: Huang, Hao, et al.
Publicado: (2016)

Neuroprotective Effects of Daphnetin against NMDA Receptor-Mediated Excitotoxicity
por: Yang, Le, et al.
Publicado: (2014)

Cynaroside inhibits Leishmania donovani UDP-galactopyranose mutase and induces reactive oxygen species to exert antileishmanial response
por: Tabrez, Shams, et al.
Publicado: (2021)

Galantamine potentiates the neuroprotective effect of memantine against NMDA-induced excitotoxicity
por: Lopes, João P, et al.
Publicado: (2013)

Neuroprotective Effect of AM404 Against NMDA-Induced Hippocampal Excitotoxicity
por: Saliba, Soraya Wilke, et al.
Publicado: (2019)

Effects of glycyrrhizin on the pharmacokinetics of nobiletin in rats and its potential mechanism
por: Wang, Hao, et al.
Publicado: (2020)

Nobiletin Delays Aging and Enhances Stress Resistance of Caenorhabditis elegans
por: Yang, Xueyan, et al.
Publicado: (2020)

Author Correction: Transdermal delivery of nobiletin using ionic liquids
por: Hattori, Tadashi, et al.
Publicado: (2020)

Effect of the Citrus Flavone Nobiletin on Circadian Rhythms and Metabolic Syndrome
por: Neba Ambe, Gael N. N., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_nh5i6gd7obgeu1pv6iu7ho7c19