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MTPA_Unet: Multi-Scale Transformer-Position Attention Retinal Vessel Segmentation Network Joint Transformer and CNN

Retinal vessel segmentation is extremely important for risk prediction and treatment of many major diseases. Therefore, accurate segmentation of blood vessel features from retinal images can help assist physicians in diagnosis and treatment. Convolutional neural networks are good at extracting local...

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Autores principales: Jiang, Yun, Liang, Jing, Cheng, Tongtong, Lin, Xin, Zhang, Yuan, Dong, Jinkun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9229851/
https://www.ncbi.nlm.nih.gov/pubmed/35746372
http://dx.doi.org/10.3390/s22124592
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author Jiang, Yun
Liang, Jing
Cheng, Tongtong
Lin, Xin
Zhang, Yuan
Dong, Jinkun
author_facet Jiang, Yun
Liang, Jing
Cheng, Tongtong
Lin, Xin
Zhang, Yuan
Dong, Jinkun
author_sort Jiang, Yun
collection PubMed
description Retinal vessel segmentation is extremely important for risk prediction and treatment of many major diseases. Therefore, accurate segmentation of blood vessel features from retinal images can help assist physicians in diagnosis and treatment. Convolutional neural networks are good at extracting local feature information, but the convolutional block receptive field is limited. Transformer, on the other hand, performs well in modeling long-distance dependencies. Therefore, in this paper, a new network model MTPA_Unet is designed from the perspective of extracting connections between local detailed features and making complements using long-distance dependency information, which is applied to the retinal vessel segmentation task. MTPA_Unet uses multi-resolution image input to enable the network to extract information at different levels. The proposed TPA module not only captures long-distance dependencies, but also focuses on the location information of the vessel pixels to facilitate capillary segmentation. The Transformer is combined with the convolutional neural network in a serial approach, and the original MSA module is replaced by the TPA module to achieve finer segmentation. Finally, the network model is evaluated and analyzed on three recognized retinal image datasets DRIVE, CHASE DB1, and STARE. The evaluation metrics were 0.9718, 0.9762, and 0.9773 for accuracy; 0.8410, 0.8437, and 0.8938 for sensitivity; and 0.8318, 0.8164, and 0.8557 for Dice coefficient. Compared with existing retinal image segmentation methods, the proposed method in this paper achieved better vessel segmentation in all of the publicly available fundus datasets tested performance and results.
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spelling pubmed-92298512022-06-25 MTPA_Unet: Multi-Scale Transformer-Position Attention Retinal Vessel Segmentation Network Joint Transformer and CNN Jiang, Yun Liang, Jing Cheng, Tongtong Lin, Xin Zhang, Yuan Dong, Jinkun Sensors (Basel) Article Retinal vessel segmentation is extremely important for risk prediction and treatment of many major diseases. Therefore, accurate segmentation of blood vessel features from retinal images can help assist physicians in diagnosis and treatment. Convolutional neural networks are good at extracting local feature information, but the convolutional block receptive field is limited. Transformer, on the other hand, performs well in modeling long-distance dependencies. Therefore, in this paper, a new network model MTPA_Unet is designed from the perspective of extracting connections between local detailed features and making complements using long-distance dependency information, which is applied to the retinal vessel segmentation task. MTPA_Unet uses multi-resolution image input to enable the network to extract information at different levels. The proposed TPA module not only captures long-distance dependencies, but also focuses on the location information of the vessel pixels to facilitate capillary segmentation. The Transformer is combined with the convolutional neural network in a serial approach, and the original MSA module is replaced by the TPA module to achieve finer segmentation. Finally, the network model is evaluated and analyzed on three recognized retinal image datasets DRIVE, CHASE DB1, and STARE. The evaluation metrics were 0.9718, 0.9762, and 0.9773 for accuracy; 0.8410, 0.8437, and 0.8938 for sensitivity; and 0.8318, 0.8164, and 0.8557 for Dice coefficient. Compared with existing retinal image segmentation methods, the proposed method in this paper achieved better vessel segmentation in all of the publicly available fundus datasets tested performance and results. MDPI 2022-06-17 /pmc/articles/PMC9229851/ /pubmed/35746372 http://dx.doi.org/10.3390/s22124592 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Jiang, Yun
Liang, Jing
Cheng, Tongtong
Lin, Xin
Zhang, Yuan
Dong, Jinkun
MTPA_Unet: Multi-Scale Transformer-Position Attention Retinal Vessel Segmentation Network Joint Transformer and CNN
title MTPA_Unet: Multi-Scale Transformer-Position Attention Retinal Vessel Segmentation Network Joint Transformer and CNN
title_full MTPA_Unet: Multi-Scale Transformer-Position Attention Retinal Vessel Segmentation Network Joint Transformer and CNN
title_fullStr MTPA_Unet: Multi-Scale Transformer-Position Attention Retinal Vessel Segmentation Network Joint Transformer and CNN
title_full_unstemmed MTPA_Unet: Multi-Scale Transformer-Position Attention Retinal Vessel Segmentation Network Joint Transformer and CNN
title_short MTPA_Unet: Multi-Scale Transformer-Position Attention Retinal Vessel Segmentation Network Joint Transformer and CNN
title_sort mtpa_unet: multi-scale transformer-position attention retinal vessel segmentation network joint transformer and cnn
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9229851/
https://www.ncbi.nlm.nih.gov/pubmed/35746372
http://dx.doi.org/10.3390/s22124592
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