Cargando…

Identification and clinical validation of NUSAP1 as a novel prognostic biomarker in ovarian cancer

BACKGROUND: Nucleolar and spindle-associated protein 1 (NUSAP1) was shown to be involved in cell cycle regulation in cancer. However, its prognostic value and underlying mechanism in ovarian cancer remain unclear. METHODS: Oncomine, TCGA, CCLE, and UALCAN databases were used to analyze the expressio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gou, Rui, Zheng, Mingjun, Hu, Yuexin, Gao, Lingling, Wang, Shuang, Liu, Ouxuan, Li, Xiao, Zhu, Liancheng, Liu, Juanjuan, Lin, Bei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9229913/ https://www.ncbi.nlm.nih.gov/pubmed/35739489 http://dx.doi.org/10.1186/s12885-022-09753-4

Ejemplares similares

Annexin A8 can serve as potential prognostic biomarker and therapeutic target for ovarian cancer: based on the comprehensive analysis of Annexins
por: Gou, Rui, et al.
Publicado: (2019)

Identification of the prognostic value of a 2-gene signature of the WNT gene family in UCEC using bioinformatics and real-world data
por: Hu, Yuexin, et al.
Publicado: (2021)

PGK1 Is a Key Target for Anti-Glycolytic Therapy of Ovarian Cancer: Based on the Comprehensive Analysis of Glycolysis-Related Genes
por: Gou, Rui, et al.
Publicado: (2021)

Identification of immune‐enhanced molecular subtype associated with BRCA1 mutations, immune checkpoints and clinical outcome in ovarian carcinoma
por: Zheng, Mingjun, et al.
Publicado: (2020)

Oxidative Stress Response Biomarkers of Ovarian Cancer Based on Single-Cell and Bulk RNA Sequencing
por: Zheng, Mingjun, et al.
Publicado: (2023)

ZNF703 promotes tumor progression in ovarian cancer by interacting with HE4 and epigenetically regulating PEA15
por: Wang, Shuang, et al.
Publicado: (2020)

RAD21 Confers Poor Prognosis and Affects Ovarian Cancer Sensitivity to Poly(ADP-Ribose)Polymerase Inhibitors Through DNA Damage Repair
por: Gou, Rui, et al.
Publicado: (2022)

Prognostic biomarker MCP-4 triggers epithelial-mesenchymal transition via the p38 MAPK pathway in ovarian cancer
por: Li, Siting, et al.
Publicado: (2022)

YWHAE as an HE4 interacting protein can influence the malignant behaviour of ovarian cancer by regulating the PI3K/AKT and MAPK pathways
por: Li, Xiao, et al.
Publicado: (2021)

HERPUD1 promotes ovarian cancer cell survival by sustaining autophagy and inhibit apoptosis via PI3K/AKT/mTOR and p38 MAPK signaling pathways
por: Nie, Xin, et al.
Publicado: (2022)

Keratin 80 regulated by miR-206/ETS1 promotes tumor progression via the MEK/ERK pathway in ovarian cancer
por: Liu, Ouxuan, et al.
Publicado: (2021)

Down-regulation of TRIB3 inhibits the progression of ovarian cancer via MEK/ERK signaling pathway
por: Wang, Shuang, et al.
Publicado: (2020)

Identification of PKP 2/3 as potential biomarkers of ovarian cancer based on bioinformatics and experiments
por: Gao, Lingling, et al.
Publicado: (2020)

PSMD8 can serve as potential biomarker and therapeutic target of the PSMD family in ovarian cancer: based on bioinformatics analysis and in vitro validation
por: Li, Xiao, et al.
Publicado: (2023)

Integrated multi-omics analysis of genomics, epigenomics, and transcriptomics in ovarian carcinoma
por: Zheng, Mingjun, et al.
Publicado: (2019)

Identification of long noncoding RNA RP11-89K21.1 and RP11-357H14.17 as prognostic signature of endometrial carcinoma via integrated bioinformatics analysis
por: Gao, Lingling, et al.
Publicado: (2020)

Overexpression of TMEFF1 in Endometrial Carcinoma and the Mechanism Underlying its Promotion of Malignant Behavior in Cancer Cells
por: Nie, Xin, et al.
Publicado: (2021)

Interaction of CD147 and human epididymis protein 4 promotes invasion and metastasis of ovarian cancer
por: Gao, Lingling, et al.
Publicado: (2021)

Development of a seven-gene tumor immune microenvironment prognostic signature for high-risk grade III endometrial cancer
por: Zheng, Mingjun, et al.
Publicado: (2021)

MCM2 and NUSAP1 Are Potential Biomarkers for the Diagnosis and Prognosis of Pancreatic Cancer
por: Deng, Yajun, et al.
Publicado: (2020)

Low BCL9 expression inhibited ovarian epithelial malignant tumor progression by decreasing proliferation, migration, and increasing apoptosis to cancer cells
por: Wang, Jing, et al.
Publicado: (2019)

Exosomal ANXA2 derived from ovarian cancer cells regulates epithelial‐mesenchymal plasticity of human peritoneal mesothelial cells
por: Gao, Lingling, et al.
Publicado: (2021)

Whole Genome Analysis and Prognostic Model Construction Based on Alternative Splicing Events in Endometrial Cancer
por: Wang, Caixia, et al.
Publicado: (2019)

Gene expression profile analysis identifies metastasis and chemoresistance-associated genes in epithelial ovarian carcinoma cells
por: Zhu, Liancheng, et al.
Publicado: (2014)

NUSAP1 promotes invasion and metastasis of prostate cancer
por: Gordon, Catherine A., et al.
Publicado: (2017)

Chemoresistance Is Associated with MUC1 and Lewis y Antigen Expression in Ovarian Epithelial Cancers
por: Zhang, Danye, et al.
Publicado: (2013)

Comprehensive pan-cancer analysis reveals NUSAP1 is a novel predictive biomarker for prognosis and immunotherapy response
por: Zheng, Hong, et al.
Publicado: (2023)

Evaluate the diagnostic and prognostic value of NUSAP1 in papillary thyroid carcinoma and identify the relationship with genes, proteins, and immune factors
por: Gao, Tiantian, et al.
Publicado: (2022)

NUSAP1 promotes the metastasis of breast cancer cells via the AMPK/PPARγ signaling pathway
por: Qiu, Juanjuan, et al.
Publicado: (2021)

The fucosylated CD147 enhances the autophagy in epithelial ovarian cancer cells
por: Hu, Zhenhua, et al.
Publicado: (2016)

Nucleolar and Spindle Associated Protein 1 (NUSAP1) Promotes Bladder Cancer Progression Through the TGF-β Signaling Pathway
por: Gao, Shun, et al.
Publicado: (2020)

Human epididymis protein 4 in association with Annexin II promotes invasion and metastasis of ovarian cancer cells
por: Zhuang, Huiyu, et al.
Publicado: (2014)

RNA-Binding Protein COL14A1, TNS1, NUSAP1 and YWHAE Are Valid Biomarkers to Predict Peritoneal Metastasis in Gastric Cancer
por: Jiang, Yue, et al.
Publicado: (2022)

O-GlcNAcylation Enhances NUSAP1 Stability and Promotes Bladder Cancer Aggressiveness
por: Chen, Yifan, et al.
Publicado: (2021)

MRPL15 is a novel prognostic biomarker and therapeutic target for epithelial ovarian cancer
por: Xu, Haoya, et al.
Publicado: (2021)

c-Fos mediates α1, 2-fucosyltransferase 1 and Lewis y expression in response to TGF-β1 in ovarian cancer
por: Hao, Yingying, et al.
Publicado: (2017)

NuSAP modulates the dynamics of kinetochore microtubules by attenuating MCAK depolymerisation activity
por: Li, Chenyu, et al.
Publicado: (2016)

Decreased Expression of NUSAP1 Predicts Poor Overall Survival in Cervical Cancer
por: Xie, Qiqi, et al.
Publicado: (2020)

SERPIND1 Affects the Malignant Biological Behavior of Epithelial Ovarian Cancer via the PI3K/AKT Pathway: A Mechanistic Study
por: Guo, Qian, et al.
Publicado: (2019)

Alternatively activated NUSAP1 promotes tumor growth and indicates poor prognosis in hepatocellular carcinoma
por: Shi, Chao, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_nvrrdj4hjuesqmhv00iae1ek45