Development of Reduced Peptide Bond Pseudopeptide Michael Acceptors for the Treatment of Human African Trypanosomiasis

Human African Trypanosomiasis (HAT) is an endemic protozoan disease widespread in the sub-Saharan region that is caused by T. b. gambiense and T. b. rhodesiense. The development of molecules targeting rhodesain, the main cysteine protease of T. b. rhodesiense, has led to a panel of inhibitors endowe...

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Detalles Bibliográficos
Autores principales: Previti, Santo, Ettari, Roberta, Di Chio, Carla, Ravichandran, Rahul, Bogacz, Marta, Hellmich, Ute A., Schirmeister, Tanja, Cosconati, Sandro, Zappalà, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9229991/
https://www.ncbi.nlm.nih.gov/pubmed/35744891
http://dx.doi.org/10.3390/molecules27123765

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