Intrinsic antiviral immunity of barrier cells revealed by an iPSC-derived blood-brain barrier cellular model

Physiological blood-tissue barriers play a critical role in separating the circulation from immune-privileged sites and denying access to blood-borne viruses. The mechanism of virus restriction by these barriers is poorly understood. We utilize induced pluripotent stem cell (iPSC)-derived human brai...

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Detalles Bibliográficos
Autores principales: Cheng, Yichen, Medina, Angelica, Yao, Zhenlan, Basu, Mausumi, Natekar, Janhavi P., Lang, Jianshe, Sanchez, Egan, Nkembo, Mezindia B., Xu, Chongchong, Qian, Xuyu, Nguyen, Phuong T.T., Wen, Zhexing, Song, Hongjun, Ming, Guo-Li, Kumar, Mukesh, Brinton, Margo A., Li, Melody M.H., Tang, Hengli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9230077/
https://www.ncbi.nlm.nih.gov/pubmed/35649379
http://dx.doi.org/10.1016/j.celrep.2022.110885

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