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Induction of DR5-Dependent Apoptosis by PGA(2) through ATF4-CHOP Pathway

Prostaglandin (PG) A(2), a cyclopentenone PG, induced apoptosis in both HCT116 and HCT116 p53 −/− cells. Although PGA(2)-induced apoptosis in HCT116 cells was dependent on the p53-DR5 pathway, the mechanism underlying PGA(2)-induced apoptosis in HCT116 p53 −/− cells remains unknown. In this study, w...

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Detalles Bibliográficos
Autores principales:	Park, Kyeong-Min, Park, Ji-Young, Pyo, Jaehyuk, Lee, Sun-Young, Kim, Ho-Shik
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9230093/ https://www.ncbi.nlm.nih.gov/pubmed/35744931 http://dx.doi.org/10.3390/molecules27123804

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