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Peptides to Overcome the Limitations of Current Anticancer and Antimicrobial Nanotherapies

Biomedical research devotes a huge effort to the development of efficient non-viral nanovectors (NV) to improve the effectiveness of standard therapies. NVs should be stable, sustainable and biocompatible and enable controlled and targeted delivery of drugs. With the aim to foster the advancements o...

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Detalles Bibliográficos
Autores principales: Del Genio, Valentina, Bellavita, Rosa, Falanga, Annarita, Hervé-Aubert, Katel, Chourpa, Igor, Galdiero, Stefania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9230615/
https://www.ncbi.nlm.nih.gov/pubmed/35745807
http://dx.doi.org/10.3390/pharmaceutics14061235
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author Del Genio, Valentina
Bellavita, Rosa
Falanga, Annarita
Hervé-Aubert, Katel
Chourpa, Igor
Galdiero, Stefania
author_facet Del Genio, Valentina
Bellavita, Rosa
Falanga, Annarita
Hervé-Aubert, Katel
Chourpa, Igor
Galdiero, Stefania
author_sort Del Genio, Valentina
collection PubMed
description Biomedical research devotes a huge effort to the development of efficient non-viral nanovectors (NV) to improve the effectiveness of standard therapies. NVs should be stable, sustainable and biocompatible and enable controlled and targeted delivery of drugs. With the aim to foster the advancements of such devices, this review reports some recent results applicable to treat two types of pathologies, cancer and microbial infections, aiming to provide guidance in the overall design of personalized nanomedicines and highlight the key role played by peptides in this field. Additionally, future challenges and potential perspectives are illustrated, in the hope of accelerating the translational advances of nanomedicine
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spelling pubmed-92306152022-06-25 Peptides to Overcome the Limitations of Current Anticancer and Antimicrobial Nanotherapies Del Genio, Valentina Bellavita, Rosa Falanga, Annarita Hervé-Aubert, Katel Chourpa, Igor Galdiero, Stefania Pharmaceutics Review Biomedical research devotes a huge effort to the development of efficient non-viral nanovectors (NV) to improve the effectiveness of standard therapies. NVs should be stable, sustainable and biocompatible and enable controlled and targeted delivery of drugs. With the aim to foster the advancements of such devices, this review reports some recent results applicable to treat two types of pathologies, cancer and microbial infections, aiming to provide guidance in the overall design of personalized nanomedicines and highlight the key role played by peptides in this field. Additionally, future challenges and potential perspectives are illustrated, in the hope of accelerating the translational advances of nanomedicine MDPI 2022-06-10 /pmc/articles/PMC9230615/ /pubmed/35745807 http://dx.doi.org/10.3390/pharmaceutics14061235 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Del Genio, Valentina
Bellavita, Rosa
Falanga, Annarita
Hervé-Aubert, Katel
Chourpa, Igor
Galdiero, Stefania
Peptides to Overcome the Limitations of Current Anticancer and Antimicrobial Nanotherapies
title Peptides to Overcome the Limitations of Current Anticancer and Antimicrobial Nanotherapies
title_full Peptides to Overcome the Limitations of Current Anticancer and Antimicrobial Nanotherapies
title_fullStr Peptides to Overcome the Limitations of Current Anticancer and Antimicrobial Nanotherapies
title_full_unstemmed Peptides to Overcome the Limitations of Current Anticancer and Antimicrobial Nanotherapies
title_short Peptides to Overcome the Limitations of Current Anticancer and Antimicrobial Nanotherapies
title_sort peptides to overcome the limitations of current anticancer and antimicrobial nanotherapies
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9230615/
https://www.ncbi.nlm.nih.gov/pubmed/35745807
http://dx.doi.org/10.3390/pharmaceutics14061235
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