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Peptides to Overcome the Limitations of Current Anticancer and Antimicrobial Nanotherapies
Biomedical research devotes a huge effort to the development of efficient non-viral nanovectors (NV) to improve the effectiveness of standard therapies. NVs should be stable, sustainable and biocompatible and enable controlled and targeted delivery of drugs. With the aim to foster the advancements o...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9230615/ https://www.ncbi.nlm.nih.gov/pubmed/35745807 http://dx.doi.org/10.3390/pharmaceutics14061235 |
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author | Del Genio, Valentina Bellavita, Rosa Falanga, Annarita Hervé-Aubert, Katel Chourpa, Igor Galdiero, Stefania |
author_facet | Del Genio, Valentina Bellavita, Rosa Falanga, Annarita Hervé-Aubert, Katel Chourpa, Igor Galdiero, Stefania |
author_sort | Del Genio, Valentina |
collection | PubMed |
description | Biomedical research devotes a huge effort to the development of efficient non-viral nanovectors (NV) to improve the effectiveness of standard therapies. NVs should be stable, sustainable and biocompatible and enable controlled and targeted delivery of drugs. With the aim to foster the advancements of such devices, this review reports some recent results applicable to treat two types of pathologies, cancer and microbial infections, aiming to provide guidance in the overall design of personalized nanomedicines and highlight the key role played by peptides in this field. Additionally, future challenges and potential perspectives are illustrated, in the hope of accelerating the translational advances of nanomedicine |
format | Online Article Text |
id | pubmed-9230615 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-92306152022-06-25 Peptides to Overcome the Limitations of Current Anticancer and Antimicrobial Nanotherapies Del Genio, Valentina Bellavita, Rosa Falanga, Annarita Hervé-Aubert, Katel Chourpa, Igor Galdiero, Stefania Pharmaceutics Review Biomedical research devotes a huge effort to the development of efficient non-viral nanovectors (NV) to improve the effectiveness of standard therapies. NVs should be stable, sustainable and biocompatible and enable controlled and targeted delivery of drugs. With the aim to foster the advancements of such devices, this review reports some recent results applicable to treat two types of pathologies, cancer and microbial infections, aiming to provide guidance in the overall design of personalized nanomedicines and highlight the key role played by peptides in this field. Additionally, future challenges and potential perspectives are illustrated, in the hope of accelerating the translational advances of nanomedicine MDPI 2022-06-10 /pmc/articles/PMC9230615/ /pubmed/35745807 http://dx.doi.org/10.3390/pharmaceutics14061235 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Del Genio, Valentina Bellavita, Rosa Falanga, Annarita Hervé-Aubert, Katel Chourpa, Igor Galdiero, Stefania Peptides to Overcome the Limitations of Current Anticancer and Antimicrobial Nanotherapies |
title | Peptides to Overcome the Limitations of Current Anticancer and Antimicrobial Nanotherapies |
title_full | Peptides to Overcome the Limitations of Current Anticancer and Antimicrobial Nanotherapies |
title_fullStr | Peptides to Overcome the Limitations of Current Anticancer and Antimicrobial Nanotherapies |
title_full_unstemmed | Peptides to Overcome the Limitations of Current Anticancer and Antimicrobial Nanotherapies |
title_short | Peptides to Overcome the Limitations of Current Anticancer and Antimicrobial Nanotherapies |
title_sort | peptides to overcome the limitations of current anticancer and antimicrobial nanotherapies |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9230615/ https://www.ncbi.nlm.nih.gov/pubmed/35745807 http://dx.doi.org/10.3390/pharmaceutics14061235 |
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