Combined Transcriptomic and Proteomic Profiling to Unravel Osimertinib, CARP-1 Functional Mimetic (CFM 4.17) Formulation and Telmisartan Combo Treatment in NSCLC Tumor Xenografts

The epidermal growth factor receptor (EGFR) is highly expressed in many non-small cell lung cancers (NSCLC), necessitating the use of EGFR-tyrosine kinase inhibitors (TKIs) as first-line treatments. Osimertinib (OSM), a third-generation TKI, is routinely used in clinics, but T790M mutations in exon...

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Detalles Bibliográficos
Autores principales: Nimma, Ramesh, Kalvala, Anil Kumar, Patel, Nilkumar, Surapaneni, Sunil Kumar, Sun, Li, Singh, Rakesh, Nottingham, Ebony, Bagde, Arvind, Kommineni, Nagavendra, Arthur, Peggy, Nathani, Aakash, Meckes, David G., Singh, Mandip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9230742/
https://www.ncbi.nlm.nih.gov/pubmed/35745729
http://dx.doi.org/10.3390/pharmaceutics14061156

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