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Multi-Label Fundus Image Classification Using Attention Mechanisms and Feature Fusion
Fundus diseases can cause irreversible vision loss in both eyes if not diagnosed and treated immediately. Due to the complexity of fundus diseases, the probability of fundus images containing two or more diseases is extremely high, while existing deep learning-based fundus image classification algor...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9230753/ https://www.ncbi.nlm.nih.gov/pubmed/35744561 http://dx.doi.org/10.3390/mi13060947 |
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author | Li, Zhenwei Xu, Mengying Yang, Xiaoli Han, Yanqi |
author_facet | Li, Zhenwei Xu, Mengying Yang, Xiaoli Han, Yanqi |
author_sort | Li, Zhenwei |
collection | PubMed |
description | Fundus diseases can cause irreversible vision loss in both eyes if not diagnosed and treated immediately. Due to the complexity of fundus diseases, the probability of fundus images containing two or more diseases is extremely high, while existing deep learning-based fundus image classification algorithms have low diagnostic accuracy in multi-labeled fundus images. In this paper, a multi-label classification of fundus disease with binocular fundus images is presented, using a neural network algorithm model based on attention mechanisms and feature fusion. The algorithm highlights detailed features in binocular fundus images, and then feeds them into a ResNet50 network with attention mechanisms to extract fundus image lesion features. The model obtains global features of binocular images through feature fusion and uses Softmax to classify multi-label fundus images. The ODIR binocular fundus image dataset was used to evaluate the network classification performance and conduct ablation experiments. The model’s backend is the Tensorflow framework. Through experiments on the test images, this method achieved accuracy, precision, recall, and F1 values of 94.23%, 99.09%, 99.23%, and 99.16%, respectively. |
format | Online Article Text |
id | pubmed-9230753 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-92307532022-06-25 Multi-Label Fundus Image Classification Using Attention Mechanisms and Feature Fusion Li, Zhenwei Xu, Mengying Yang, Xiaoli Han, Yanqi Micromachines (Basel) Article Fundus diseases can cause irreversible vision loss in both eyes if not diagnosed and treated immediately. Due to the complexity of fundus diseases, the probability of fundus images containing two or more diseases is extremely high, while existing deep learning-based fundus image classification algorithms have low diagnostic accuracy in multi-labeled fundus images. In this paper, a multi-label classification of fundus disease with binocular fundus images is presented, using a neural network algorithm model based on attention mechanisms and feature fusion. The algorithm highlights detailed features in binocular fundus images, and then feeds them into a ResNet50 network with attention mechanisms to extract fundus image lesion features. The model obtains global features of binocular images through feature fusion and uses Softmax to classify multi-label fundus images. The ODIR binocular fundus image dataset was used to evaluate the network classification performance and conduct ablation experiments. The model’s backend is the Tensorflow framework. Through experiments on the test images, this method achieved accuracy, precision, recall, and F1 values of 94.23%, 99.09%, 99.23%, and 99.16%, respectively. MDPI 2022-06-15 /pmc/articles/PMC9230753/ /pubmed/35744561 http://dx.doi.org/10.3390/mi13060947 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Li, Zhenwei Xu, Mengying Yang, Xiaoli Han, Yanqi Multi-Label Fundus Image Classification Using Attention Mechanisms and Feature Fusion |
title | Multi-Label Fundus Image Classification Using Attention Mechanisms and Feature Fusion |
title_full | Multi-Label Fundus Image Classification Using Attention Mechanisms and Feature Fusion |
title_fullStr | Multi-Label Fundus Image Classification Using Attention Mechanisms and Feature Fusion |
title_full_unstemmed | Multi-Label Fundus Image Classification Using Attention Mechanisms and Feature Fusion |
title_short | Multi-Label Fundus Image Classification Using Attention Mechanisms and Feature Fusion |
title_sort | multi-label fundus image classification using attention mechanisms and feature fusion |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9230753/ https://www.ncbi.nlm.nih.gov/pubmed/35744561 http://dx.doi.org/10.3390/mi13060947 |
work_keys_str_mv | AT lizhenwei multilabelfundusimageclassificationusingattentionmechanismsandfeaturefusion AT xumengying multilabelfundusimageclassificationusingattentionmechanismsandfeaturefusion AT yangxiaoli multilabelfundusimageclassificationusingattentionmechanismsandfeaturefusion AT hanyanqi multilabelfundusimageclassificationusingattentionmechanismsandfeaturefusion |