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Hepatitis C Virus Epidemiology in Lithuania: Situation before Introduction of the National Screening Programme

In 2022, the Lithuanian health authorities decided to pay general practitioners a fee for performing serological tests for hepatitis C virus (HCV) antibodies in the population born from 1945 to 1994 once per life and annual HCV testing for PWID and HIV infected patients. This study aimed to assess t...

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Autores principales: Ciupkeviciene, Egle, Petkeviciene, Janina, Sumskiene, Jolanta, Dragunas, Gediminas, Dabravalskis, Saulius, Kreivenaite, Edita, Telksnys, Tadas, Urbonas, Gediminas, Kupcinskas, Limas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9230764/
https://www.ncbi.nlm.nih.gov/pubmed/35746663
http://dx.doi.org/10.3390/v14061192
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author Ciupkeviciene, Egle
Petkeviciene, Janina
Sumskiene, Jolanta
Dragunas, Gediminas
Dabravalskis, Saulius
Kreivenaite, Edita
Telksnys, Tadas
Urbonas, Gediminas
Kupcinskas, Limas
author_facet Ciupkeviciene, Egle
Petkeviciene, Janina
Sumskiene, Jolanta
Dragunas, Gediminas
Dabravalskis, Saulius
Kreivenaite, Edita
Telksnys, Tadas
Urbonas, Gediminas
Kupcinskas, Limas
author_sort Ciupkeviciene, Egle
collection PubMed
description In 2022, the Lithuanian health authorities decided to pay general practitioners a fee for performing serological tests for hepatitis C virus (HCV) antibodies in the population born from 1945 to 1994 once per life and annual HCV testing for PWID and HIV infected patients. This study aimed to assess trends in HCV-related mortality in the country and the prevalence of HCV infection among patients with liver diseases and evaluate possibilities of screening for HCV infection at a primary health care center. Age-standardized mortality rates in 2010–2020 were calculated for deaths caused by chronic hepatitis C and some liver diseases. Data on HCV infection among patients with liver cirrhosis, cancer and transplant patients were collected from the tertiary care hospital Kauno Klinikos. The prevalence of anti-HCV and risk factors of HCV infection was assessed among patients registered with the health care center in Klaipeda, where a pilot study of screening was performed. No steady trend in mortality was observed. Analysis of medical documentation showed that 40.5% of patients with liver cirrhosis, 49.7% with cancers and 36.9% of transplant patients were HCV infected. Over the year, 4867 patients were screened in the primary health care center. Positive anti-HCV prevalence was 1.7% (2.1% in men and 1.3% in women). Blood transfusion and being a blood donor before 1993 also having tattoos were associated with higher odds of HCV infection. The study revealed the active participation of individuals in HCV screening.
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spelling pubmed-92307642022-06-25 Hepatitis C Virus Epidemiology in Lithuania: Situation before Introduction of the National Screening Programme Ciupkeviciene, Egle Petkeviciene, Janina Sumskiene, Jolanta Dragunas, Gediminas Dabravalskis, Saulius Kreivenaite, Edita Telksnys, Tadas Urbonas, Gediminas Kupcinskas, Limas Viruses Article In 2022, the Lithuanian health authorities decided to pay general practitioners a fee for performing serological tests for hepatitis C virus (HCV) antibodies in the population born from 1945 to 1994 once per life and annual HCV testing for PWID and HIV infected patients. This study aimed to assess trends in HCV-related mortality in the country and the prevalence of HCV infection among patients with liver diseases and evaluate possibilities of screening for HCV infection at a primary health care center. Age-standardized mortality rates in 2010–2020 were calculated for deaths caused by chronic hepatitis C and some liver diseases. Data on HCV infection among patients with liver cirrhosis, cancer and transplant patients were collected from the tertiary care hospital Kauno Klinikos. The prevalence of anti-HCV and risk factors of HCV infection was assessed among patients registered with the health care center in Klaipeda, where a pilot study of screening was performed. No steady trend in mortality was observed. Analysis of medical documentation showed that 40.5% of patients with liver cirrhosis, 49.7% with cancers and 36.9% of transplant patients were HCV infected. Over the year, 4867 patients were screened in the primary health care center. Positive anti-HCV prevalence was 1.7% (2.1% in men and 1.3% in women). Blood transfusion and being a blood donor before 1993 also having tattoos were associated with higher odds of HCV infection. The study revealed the active participation of individuals in HCV screening. MDPI 2022-05-30 /pmc/articles/PMC9230764/ /pubmed/35746663 http://dx.doi.org/10.3390/v14061192 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Ciupkeviciene, Egle
Petkeviciene, Janina
Sumskiene, Jolanta
Dragunas, Gediminas
Dabravalskis, Saulius
Kreivenaite, Edita
Telksnys, Tadas
Urbonas, Gediminas
Kupcinskas, Limas
Hepatitis C Virus Epidemiology in Lithuania: Situation before Introduction of the National Screening Programme
title Hepatitis C Virus Epidemiology in Lithuania: Situation before Introduction of the National Screening Programme
title_full Hepatitis C Virus Epidemiology in Lithuania: Situation before Introduction of the National Screening Programme
title_fullStr Hepatitis C Virus Epidemiology in Lithuania: Situation before Introduction of the National Screening Programme
title_full_unstemmed Hepatitis C Virus Epidemiology in Lithuania: Situation before Introduction of the National Screening Programme
title_short Hepatitis C Virus Epidemiology in Lithuania: Situation before Introduction of the National Screening Programme
title_sort hepatitis c virus epidemiology in lithuania: situation before introduction of the national screening programme
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9230764/
https://www.ncbi.nlm.nih.gov/pubmed/35746663
http://dx.doi.org/10.3390/v14061192
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