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Pore-Forming Cardiotoxin VVA2 (Volvatoxin A2) Variant I82E/L86K Is an Atypical Duplex-Specific Nuclease

VVA2 (volvatoxin A chain 2) is a cardiotoxic protein purified from Volvariella volvacea. Its biological activities include hemolysis, writhing reaction, neurotoxicity, and ventricular systolic arresting activity. The cytotoxicity of VVA2 was mainly considered due to its pore-forming activity. Here w...

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Detalles Bibliográficos
Autores principales:	Lu, Jia-Qi, Shou, Jia-Wen, Lo, Ka-Ching, Tang, Yun-Sang, Shi, Wei-Wei, Shaw, Pang-Chui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9230820/ https://www.ncbi.nlm.nih.gov/pubmed/35737053 http://dx.doi.org/10.3390/toxins14060392

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