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Solid Dispersions Incorporated into PVP Films for the Controlled Release of Trans-Resveratrol: Development, Physicochemical and In Vitro Characterizations and In Vivo Cutaneous Anti-Inflammatory Evaluation
Trans-resveratrol can promote various dermatological effects. However, its high crystallinity decreases its solubility and bioavailability. Therefore, solid dispersions have been developed to promote its amorphization; even so, they present as powders, making cutaneous controlled drug delivery unfea...
Autores principales: | Riccio, Bruno Vincenzo Fiod, do Nascimento, André Luiz Carneiro Soares, Meneguin, Andréia Bagliotti, Rodero, Camila Fernanda, Santos, Kaio Pini, Sábio, Rafael Miguel, de Annunzio, Sarah Raquel, Fontana, Carla Raquel, Barud, Hernane da Silva, Ferrari, Priscileila Colerato, Chorilli, Marlus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9230924/ https://www.ncbi.nlm.nih.gov/pubmed/35745722 http://dx.doi.org/10.3390/pharmaceutics14061149 |
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