Cargando…

Effects of Magnesium, Pyrophosphate and Phosphonates on Pyrophosphorolytic Reaction of UDP-Glucose Pyrophosphorylase

UDP-glucose pyrophosphorylase (UGPase) carries a freely reversible reaction, using glucose-1-P and UTP to produce UDP-glucose (UDPG) and pyrophosphate (PP(i)), with UDPG being essential for glycosylation reactions in all organisms including, e.g., synthesis of sucrose, cellulose and glycoproteins. I...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kleczkowski, Leszek A., Decker, Daniel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9230926/ https://www.ncbi.nlm.nih.gov/pubmed/35736762 http://dx.doi.org/10.3390/plants11121611

Ejemplares similares

Exploring Redox Modulation of Plant UDP-Glucose Pyrophosphorylase
por: Decker, Daniel, et al.
Publicado: (2023)

Substrate Specificity and Inhibitor Sensitivity of Plant UDP-Sugar Producing Pyrophosphorylases
por: Decker, Daniel, et al.
Publicado: (2017)

The structure-activity relationship of the salicylimide derived inhibitors of UDP-sugar producing pyrophosphorylases
por: Decker, Daniel, et al.
Publicado: (2018)

UDP-Sugar Producing Pyrophosphorylases: Distinct and Essential Enzymes With Overlapping Substrate Specificities, Providing de novo Precursors for Glycosylation Reactions
por: Decker, Daniel, et al.
Publicado: (2019)

Crystal structure and insights into the oligomeric state of UDP-glucose pyrophosphorylase from sugarcane
por: Cotrim, Camila A., et al.
Publicado: (2018)

On the Ancestral UDP-Glucose Pyrophosphorylase Activity of GalF from Escherichia coli
por: Ebrecht, Ana C., et al.
Publicado: (2015)

Screening assay for inhibitors of a recombinant Streptococcus pneumoniae UDP-glucose pyrophosphorylase
por: Zavala, Agustín, et al.
Publicado: (2017)

Immobilization of the Highly Active UDP-Glucose Pyrophosphorylase From Thermocrispum agreste Provides a Highly Efficient Biocatalyst for the Production of UDP-Glucose
por: Kumpf, Antje, et al.
Publicado: (2020)

UDP-glucose pyrophosphorylase: genome-wide identification, expression and functional analyses in Gossypium hirsutum
por: Xu, Zhongyang, et al.
Publicado: (2022)

Pyrophosphate inhibits gluconeogenesis by restricting UDP-glucose formation in vivo
por: Ferjani, Ali, et al.
Publicado: (2018)

A Chimeric UDP-Glucose Pyrophosphorylase Produced by Protein Engineering Exhibits Sensitivity to Allosteric Regulators
por: Asención Diez, Matías D., et al.
Publicado: (2013)

A mechanism-inspired UDP-N-acetylglucosamine pyrophosphorylase inhibitor
por: Raimi, Olawale G., et al.
Publicado: (2020)

Targeting Streptococcus pneumoniae UDP-glucose pyrophosphorylase (UGPase): in vitro validation of a putative inhibitor
por: Sharma, Monica, et al.
Publicado: (2020)

Leishmania major UDP-sugar pyrophosphorylase salvages galactose for glycoconjugate biosynthesis
por: Damerow, Sebastian, et al.
Publicado: (2015)

UDP-glucose pyrophosphorylase as a target for regulating carbon flux distribution and antioxidant capacity in Phaeodactylum tricornutum
por: Zhang, Ruihao, et al.
Publicado: (2023)

Facile and Stereo-Selective Synthesis of UDP-α-D-xylose and UDP-β-L-arabinose Using UDP-Sugar Pyrophosphorylase
por: Wang, JiaJia, et al.
Publicado: (2018)

UDP-glucose pyrophosphorylase 2, a regulator of glycogen synthesis and glycosylation, is critical for pancreatic cancer growth
por: Wolfe, Andrew L., et al.
Publicado: (2021)

The Trypanosome UDP-Glucose Pyrophosphorylase Is Imported by Piggybacking into Glycosomes, Where Unconventional Sugar Nucleotide Synthesis Takes Place
por: Villafraz, Oriana, et al.
Publicado: (2021)

Identification, subcellular localization, biochemical properties, and high-resolution crystal structure of Trypanosoma brucei UDP-glucose pyrophosphorylase
por: Mariño, Karina, et al.
Publicado: (2010)

Author Correction: Pyrophosphate inhibits gluconeogenesis by restricting UDP-glucose formation in vivo
por: Ferjani, Ali, et al.
Publicado: (2019)

Discovery of Novel Inhibitors Targeting Multi-UDP-hexose Pyrophosphorylases as Anticancer Agents
por: Yang, Yueqin, et al.
Publicado: (2020)

Global Analysis of UDP Glucose Pyrophosphorylase (UDPGP) Gene Family in Plants: Conserved Evolution Involved in Cell Death
por: Liu, Shuai, et al.
Publicado: (2021)

Amelioration of cold-induced sweetening in potato by RNAi mediated silencing of StUGPase encoding UDP-glucose pyrophosphorylase
por: Jaiswal, Sandeep, et al.
Publicado: (2023)

UDP-sugar pyrophosphorylase controls the activity of proceeding sugar-1-kinases enzymes
por: Geserick, Claudia, et al.
Publicado: (2013)

Cloning, Characterization, and RNA Interference Effect of the UDP-N-Acetylglucosamine Pyrophosphorylase Gene in Cnaphalocrocis medinalis
por: Zhou, Yuan-Jin, et al.
Publicado: (2021)

Genetic and structural validation of Aspergillus fumigatus UDP-N-acetylglucosamine pyrophosphorylase as an antifungal target
por: Fang, Wenxia, et al.
Publicado: (2013)

Molecular and Functional Analysis of UDP-N-Acetylglucosamine Pyrophosphorylases from the Migratory Locust, Locusta migratoria
por: Liu, Xiaojian, et al.
Publicado: (2013)

A Quaternary Mechanism Enables the Complex Biological Functions of Octameric Human UDP-glucose Pyrophosphorylase, a Key Enzyme in Cell Metabolism
por: Führing, Jana Indra, et al.
Publicado: (2015)

Defects in Galactose Metabolism and Glycoconjugate Biosynthesis in a UDP-Glucose Pyrophosphorylase-Deficient Cell Line Are Reversed by Adding Galactose to the Growth Medium
por: Durrant, Christelle, et al.
Publicado: (2020)

CryoEM analysis of the essential native UDP-glucose pyrophosphorylase from Aspergillus nidulans reveals key conformations for activity regulation and function
por: Han, Xu, et al.
Publicado: (2023)

Magnesium Signaling in Plants
por: Kleczkowski, Leszek A., et al.
Publicado: (2021)

UDP-sugar pyrophosphorylase is essential for arabinose and xylose recycling, and is required during vegetative and reproductive growth in Arabidopsis
por: Geserick, Claudia, et al.
Publicado: (2013)

Role of nuclear glycogen synthase and cytoplasmic UDP glucose pyrophosphorylase in the biosynthesis of nuclear glycogen in HD33 Ehrlich-Lettre ascites tumor cells
Publicado: (1981)

Phosphonate and Bisphosphonate Inhibitors of Farnesyl Pyrophosphate Synthases: A Structure-Guided Perspective
por: Park, Jaeok, et al.
Publicado: (2021)

Identification of Leishmania major UDP-Sugar Pyrophosphorylase Inhibitors Using Biosensor-Based Small Molecule Fragment Library Screening
por: Prakash, Ohm, et al.
Publicado: (2019)

Molecular Cloning of a Novel Glucuronokinase/Putative Pyrophosphorylase from Zebrafish Acting in an UDP-Glucuronic Acid Salvage Pathway
por: Gangl, Roman, et al.
Publicado: (2014)

On the Roles of Wheat Endosperm ADP-Glucose Pyrophosphorylase Subunits
por: Ferrero, Danisa M. L., et al.
Publicado: (2018)

Comparative computational analysis of ADP Glucose Pyrophosphorylase in plants
por: Rani, Saroj, et al.
Publicado: (2013)

INTERACTIONS BETWEEN MAGNESIUM, PYROPHOSPHATE, AND THE CONTRACTILE ELEMENTS
por: Bozler, Emil
Publicado: (1954)

Overexpression of UDP‐sugar pyrophosphorylase leads to higher sensitivity towards galactose, providing new insights into the mechanisms of galactose toxicity in plants
por: Althammer, Martina, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_b0qfdfuqcm45f7etvnr5kfmud7