The In Vitro Replication, Spread, and Oncolytic Potential of Finnish Circulating Strains of Herpes Simplex Virus Type 1

Herpes simplex virus type 1 (HSV-1) is the only FDA- and EMA- approved oncolytic virus, and accordingly, many potential oncolytic HSVs (oHSV) are in clinical development. The utilized oHSV parental strains are, however, mostly based on laboratory reference strains, which may possess a compromised cy...

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Detalles Bibliográficos
Autores principales: Kalke, Kiira, Orpana, Julius, Lasanen, Tuomas, Esparta, Olaya, Lund, Liisa M., Frejborg, Fanny, Vuorinen, Tytti, Paavilainen, Henrik, Hukkanen, Veijo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9230972/
https://www.ncbi.nlm.nih.gov/pubmed/35746761
http://dx.doi.org/10.3390/v14061290

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