Irreversible Antagonists for the Adenosine A(2B) Receptor †

Blockade of the adenosine A(2B) receptor (A(2B)AR) represents a potential novel strategy for the immunotherapy of cancer. In the present study, we designed, synthesized, and characterized irreversible A(2B)AR antagonists based on an 8-p-sulfophenylxanthine scaffold. Irreversible binding was confirme...

Descripción completa

Detalles Bibliográficos
Autores principales: Temirak, Ahmed, Schlegel, Jonathan G., Voss, Jan H., Vaaßen, Victoria J., Vielmuth, Christin, Claff, Tobias, Müller, Christa E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9231011/
https://www.ncbi.nlm.nih.gov/pubmed/35744918
http://dx.doi.org/10.3390/molecules27123792

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9231011/
https://www.ncbi.nlm.nih.gov/pubmed/35744918
http://dx.doi.org/10.3390/molecules27123792

Ejemplares similares