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Irreversible Antagonists for the Adenosine A(2B) Receptor †

Blockade of the adenosine A(2B) receptor (A(2B)AR) represents a potential novel strategy for the immunotherapy of cancer. In the present study, we designed, synthesized, and characterized irreversible A(2B)AR antagonists based on an 8-p-sulfophenylxanthine scaffold. Irreversible binding was confirme...

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Detalles Bibliográficos
Autores principales:	Temirak, Ahmed, Schlegel, Jonathan G., Voss, Jan H., Vaaßen, Victoria J., Vielmuth, Christin, Claff, Tobias, Müller, Christa E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9231011/ https://www.ncbi.nlm.nih.gov/pubmed/35744918 http://dx.doi.org/10.3390/molecules27123792

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