Cargando…

Continuous Circulation of Chikungunya Virus during COVID-19 Pandemic in Jambi, Sumatra, Indonesia

Chikungunya fever is a self-limiting viral illness that is caused by the chikungunya virus (CHIKV). CHIKV is found in multiple provinces of Indonesia, with clustered local outbreaks. This case series investigates a local chikungunya outbreak during the COVID-19 pandemic, involving two virologically...

Descripción completa

Detalles Bibliográficos
Autores principales: Santoso, Marsha Sinditia, Haryanto, Sotianingsih, Rulian, Fadil, Hayati, Rahma F., Kristiani, Amanda, Kartika, Rini, Yohan, Benediktus, Hibberd, Martin L., Sasmono, R. Tedjo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9231073/
https://www.ncbi.nlm.nih.gov/pubmed/35736970
http://dx.doi.org/10.3390/tropicalmed7060091
_version_ 1784735239593000960
author Santoso, Marsha Sinditia
Haryanto, Sotianingsih
Rulian, Fadil
Hayati, Rahma F.
Kristiani, Amanda
Kartika, Rini
Yohan, Benediktus
Hibberd, Martin L.
Sasmono, R. Tedjo
author_facet Santoso, Marsha Sinditia
Haryanto, Sotianingsih
Rulian, Fadil
Hayati, Rahma F.
Kristiani, Amanda
Kartika, Rini
Yohan, Benediktus
Hibberd, Martin L.
Sasmono, R. Tedjo
author_sort Santoso, Marsha Sinditia
collection PubMed
description Chikungunya fever is a self-limiting viral illness that is caused by the chikungunya virus (CHIKV). CHIKV is found in multiple provinces of Indonesia, with clustered local outbreaks. This case series investigates a local chikungunya outbreak during the COVID-19 pandemic, involving two virologically confirmed chikungunya cases found in Jambi, Sumatra, Indonesia in 2021 and the contact tracing of 65 people from the same neighborhood (one of which was also virologically confirmed with CHIKV). The two original cases were symptomatic with classic signs of chikungunya fever, while the CHIKV-positive neighbor was asymptomatic. Out of the 65 participants, chikungunya IgM was detected in seven (10.8%) people while chikungunya IgG was detected in six (9.2%) using capture ELISA. Dengue IgG was detected by rapid test in three (4.6%) of the participants, showcasing a history of dengue virus (DENV) infection along with the circulation of CHIKV in the area. A phylogenetic analysis demonstrates a close evolutionary relationship between all three 2021 Jambi CHIKV isolates and the 2015–2016 isolates from Jambi. This case series showcases the endemicity and persistent circulation of CHIKV in Jambi, leaving the area vulnerable to eminent outbreaks of chikungunya fever and doubling the burden of disease during the COVID-19 pandemic. Health staff training for case detection and notification, as well as an integrated vector surveillance should continue to be implemented to provide an early warning indicator of possible chikungunya outbreaks.
format Online
Article
Text
id pubmed-9231073
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-92310732022-06-25 Continuous Circulation of Chikungunya Virus during COVID-19 Pandemic in Jambi, Sumatra, Indonesia Santoso, Marsha Sinditia Haryanto, Sotianingsih Rulian, Fadil Hayati, Rahma F. Kristiani, Amanda Kartika, Rini Yohan, Benediktus Hibberd, Martin L. Sasmono, R. Tedjo Trop Med Infect Dis Case Report Chikungunya fever is a self-limiting viral illness that is caused by the chikungunya virus (CHIKV). CHIKV is found in multiple provinces of Indonesia, with clustered local outbreaks. This case series investigates a local chikungunya outbreak during the COVID-19 pandemic, involving two virologically confirmed chikungunya cases found in Jambi, Sumatra, Indonesia in 2021 and the contact tracing of 65 people from the same neighborhood (one of which was also virologically confirmed with CHIKV). The two original cases were symptomatic with classic signs of chikungunya fever, while the CHIKV-positive neighbor was asymptomatic. Out of the 65 participants, chikungunya IgM was detected in seven (10.8%) people while chikungunya IgG was detected in six (9.2%) using capture ELISA. Dengue IgG was detected by rapid test in three (4.6%) of the participants, showcasing a history of dengue virus (DENV) infection along with the circulation of CHIKV in the area. A phylogenetic analysis demonstrates a close evolutionary relationship between all three 2021 Jambi CHIKV isolates and the 2015–2016 isolates from Jambi. This case series showcases the endemicity and persistent circulation of CHIKV in Jambi, leaving the area vulnerable to eminent outbreaks of chikungunya fever and doubling the burden of disease during the COVID-19 pandemic. Health staff training for case detection and notification, as well as an integrated vector surveillance should continue to be implemented to provide an early warning indicator of possible chikungunya outbreaks. MDPI 2022-06-05 /pmc/articles/PMC9231073/ /pubmed/35736970 http://dx.doi.org/10.3390/tropicalmed7060091 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Santoso, Marsha Sinditia
Haryanto, Sotianingsih
Rulian, Fadil
Hayati, Rahma F.
Kristiani, Amanda
Kartika, Rini
Yohan, Benediktus
Hibberd, Martin L.
Sasmono, R. Tedjo
Continuous Circulation of Chikungunya Virus during COVID-19 Pandemic in Jambi, Sumatra, Indonesia
title Continuous Circulation of Chikungunya Virus during COVID-19 Pandemic in Jambi, Sumatra, Indonesia
title_full Continuous Circulation of Chikungunya Virus during COVID-19 Pandemic in Jambi, Sumatra, Indonesia
title_fullStr Continuous Circulation of Chikungunya Virus during COVID-19 Pandemic in Jambi, Sumatra, Indonesia
title_full_unstemmed Continuous Circulation of Chikungunya Virus during COVID-19 Pandemic in Jambi, Sumatra, Indonesia
title_short Continuous Circulation of Chikungunya Virus during COVID-19 Pandemic in Jambi, Sumatra, Indonesia
title_sort continuous circulation of chikungunya virus during covid-19 pandemic in jambi, sumatra, indonesia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9231073/
https://www.ncbi.nlm.nih.gov/pubmed/35736970
http://dx.doi.org/10.3390/tropicalmed7060091
work_keys_str_mv AT santosomarshasinditia continuouscirculationofchikungunyavirusduringcovid19pandemicinjambisumatraindonesia
AT haryantosotianingsih continuouscirculationofchikungunyavirusduringcovid19pandemicinjambisumatraindonesia
AT rulianfadil continuouscirculationofchikungunyavirusduringcovid19pandemicinjambisumatraindonesia
AT hayatirahmaf continuouscirculationofchikungunyavirusduringcovid19pandemicinjambisumatraindonesia
AT kristianiamanda continuouscirculationofchikungunyavirusduringcovid19pandemicinjambisumatraindonesia
AT kartikarini continuouscirculationofchikungunyavirusduringcovid19pandemicinjambisumatraindonesia
AT yohanbenediktus continuouscirculationofchikungunyavirusduringcovid19pandemicinjambisumatraindonesia
AT hibberdmartinl continuouscirculationofchikungunyavirusduringcovid19pandemicinjambisumatraindonesia
AT sasmonortedjo continuouscirculationofchikungunyavirusduringcovid19pandemicinjambisumatraindonesia