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Classification of Amino Acids Using Hybrid Terahertz Spectrum and an Efficient Channel Attention Convolutional Neural Network

Terahertz (THz) spectroscopy is the de facto method to study the vibration modes and rotational energy levels of molecules and is a widely used molecular sensor for non-destructive inspection. Here, based on the THz spectra of 20 amino acids, a method that extracts high-dimensional features from a h...

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Detalles Bibliográficos
Autores principales: Wang, Bo, Qin, Xiaoling, Meng, Kun, Zhu, Liguo, Li, Zeren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9231080/
https://www.ncbi.nlm.nih.gov/pubmed/35745458
http://dx.doi.org/10.3390/nano12122114
Descripción
Sumario:Terahertz (THz) spectroscopy is the de facto method to study the vibration modes and rotational energy levels of molecules and is a widely used molecular sensor for non-destructive inspection. Here, based on the THz spectra of 20 amino acids, a method that extracts high-dimensional features from a hybrid spectrum combined with absorption rate and refractive index is proposed. A convolutional neural network (CNN) calibrated by efficient channel attention (ECA) is designed to learn from the high-dimensional features and make classifications. The proposed method achieves an accuracy of [Formula: see text] and [Formula: see text] on two testing datasets, which are [Formula: see text] and [Formula: see text] higher than the method solely classifying the absorption spectrum. The proposed method also realizes a processing speed of 3782.46 frames per second (fps), which is the highest among all the methods in comparison. Due to the compact size, high accuracy, and high speed, the proposed method is viable for future applications in THz chemical sensors.