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Classification of Amino Acids Using Hybrid Terahertz Spectrum and an Efficient Channel Attention Convolutional Neural Network
Terahertz (THz) spectroscopy is the de facto method to study the vibration modes and rotational energy levels of molecules and is a widely used molecular sensor for non-destructive inspection. Here, based on the THz spectra of 20 amino acids, a method that extracts high-dimensional features from a h...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9231080/ https://www.ncbi.nlm.nih.gov/pubmed/35745458 http://dx.doi.org/10.3390/nano12122114 |
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author | Wang, Bo Qin, Xiaoling Meng, Kun Zhu, Liguo Li, Zeren |
author_facet | Wang, Bo Qin, Xiaoling Meng, Kun Zhu, Liguo Li, Zeren |
author_sort | Wang, Bo |
collection | PubMed |
description | Terahertz (THz) spectroscopy is the de facto method to study the vibration modes and rotational energy levels of molecules and is a widely used molecular sensor for non-destructive inspection. Here, based on the THz spectra of 20 amino acids, a method that extracts high-dimensional features from a hybrid spectrum combined with absorption rate and refractive index is proposed. A convolutional neural network (CNN) calibrated by efficient channel attention (ECA) is designed to learn from the high-dimensional features and make classifications. The proposed method achieves an accuracy of [Formula: see text] and [Formula: see text] on two testing datasets, which are [Formula: see text] and [Formula: see text] higher than the method solely classifying the absorption spectrum. The proposed method also realizes a processing speed of 3782.46 frames per second (fps), which is the highest among all the methods in comparison. Due to the compact size, high accuracy, and high speed, the proposed method is viable for future applications in THz chemical sensors. |
format | Online Article Text |
id | pubmed-9231080 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-92310802022-06-25 Classification of Amino Acids Using Hybrid Terahertz Spectrum and an Efficient Channel Attention Convolutional Neural Network Wang, Bo Qin, Xiaoling Meng, Kun Zhu, Liguo Li, Zeren Nanomaterials (Basel) Article Terahertz (THz) spectroscopy is the de facto method to study the vibration modes and rotational energy levels of molecules and is a widely used molecular sensor for non-destructive inspection. Here, based on the THz spectra of 20 amino acids, a method that extracts high-dimensional features from a hybrid spectrum combined with absorption rate and refractive index is proposed. A convolutional neural network (CNN) calibrated by efficient channel attention (ECA) is designed to learn from the high-dimensional features and make classifications. The proposed method achieves an accuracy of [Formula: see text] and [Formula: see text] on two testing datasets, which are [Formula: see text] and [Formula: see text] higher than the method solely classifying the absorption spectrum. The proposed method also realizes a processing speed of 3782.46 frames per second (fps), which is the highest among all the methods in comparison. Due to the compact size, high accuracy, and high speed, the proposed method is viable for future applications in THz chemical sensors. MDPI 2022-06-20 /pmc/articles/PMC9231080/ /pubmed/35745458 http://dx.doi.org/10.3390/nano12122114 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Wang, Bo Qin, Xiaoling Meng, Kun Zhu, Liguo Li, Zeren Classification of Amino Acids Using Hybrid Terahertz Spectrum and an Efficient Channel Attention Convolutional Neural Network |
title | Classification of Amino Acids Using Hybrid Terahertz Spectrum and an Efficient Channel Attention Convolutional Neural Network |
title_full | Classification of Amino Acids Using Hybrid Terahertz Spectrum and an Efficient Channel Attention Convolutional Neural Network |
title_fullStr | Classification of Amino Acids Using Hybrid Terahertz Spectrum and an Efficient Channel Attention Convolutional Neural Network |
title_full_unstemmed | Classification of Amino Acids Using Hybrid Terahertz Spectrum and an Efficient Channel Attention Convolutional Neural Network |
title_short | Classification of Amino Acids Using Hybrid Terahertz Spectrum and an Efficient Channel Attention Convolutional Neural Network |
title_sort | classification of amino acids using hybrid terahertz spectrum and an efficient channel attention convolutional neural network |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9231080/ https://www.ncbi.nlm.nih.gov/pubmed/35745458 http://dx.doi.org/10.3390/nano12122114 |
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