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Classification of Amino Acids Using Hybrid Terahertz Spectrum and an Efficient Channel Attention Convolutional Neural Network

Terahertz (THz) spectroscopy is the de facto method to study the vibration modes and rotational energy levels of molecules and is a widely used molecular sensor for non-destructive inspection. Here, based on the THz spectra of 20 amino acids, a method that extracts high-dimensional features from a h...

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Detalles Bibliográficos
Autores principales: Wang, Bo, Qin, Xiaoling, Meng, Kun, Zhu, Liguo, Li, Zeren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9231080/
https://www.ncbi.nlm.nih.gov/pubmed/35745458
http://dx.doi.org/10.3390/nano12122114
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author Wang, Bo
Qin, Xiaoling
Meng, Kun
Zhu, Liguo
Li, Zeren
author_facet Wang, Bo
Qin, Xiaoling
Meng, Kun
Zhu, Liguo
Li, Zeren
author_sort Wang, Bo
collection PubMed
description Terahertz (THz) spectroscopy is the de facto method to study the vibration modes and rotational energy levels of molecules and is a widely used molecular sensor for non-destructive inspection. Here, based on the THz spectra of 20 amino acids, a method that extracts high-dimensional features from a hybrid spectrum combined with absorption rate and refractive index is proposed. A convolutional neural network (CNN) calibrated by efficient channel attention (ECA) is designed to learn from the high-dimensional features and make classifications. The proposed method achieves an accuracy of [Formula: see text] and [Formula: see text] on two testing datasets, which are [Formula: see text] and [Formula: see text] higher than the method solely classifying the absorption spectrum. The proposed method also realizes a processing speed of 3782.46 frames per second (fps), which is the highest among all the methods in comparison. Due to the compact size, high accuracy, and high speed, the proposed method is viable for future applications in THz chemical sensors.
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spelling pubmed-92310802022-06-25 Classification of Amino Acids Using Hybrid Terahertz Spectrum and an Efficient Channel Attention Convolutional Neural Network Wang, Bo Qin, Xiaoling Meng, Kun Zhu, Liguo Li, Zeren Nanomaterials (Basel) Article Terahertz (THz) spectroscopy is the de facto method to study the vibration modes and rotational energy levels of molecules and is a widely used molecular sensor for non-destructive inspection. Here, based on the THz spectra of 20 amino acids, a method that extracts high-dimensional features from a hybrid spectrum combined with absorption rate and refractive index is proposed. A convolutional neural network (CNN) calibrated by efficient channel attention (ECA) is designed to learn from the high-dimensional features and make classifications. The proposed method achieves an accuracy of [Formula: see text] and [Formula: see text] on two testing datasets, which are [Formula: see text] and [Formula: see text] higher than the method solely classifying the absorption spectrum. The proposed method also realizes a processing speed of 3782.46 frames per second (fps), which is the highest among all the methods in comparison. Due to the compact size, high accuracy, and high speed, the proposed method is viable for future applications in THz chemical sensors. MDPI 2022-06-20 /pmc/articles/PMC9231080/ /pubmed/35745458 http://dx.doi.org/10.3390/nano12122114 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Wang, Bo
Qin, Xiaoling
Meng, Kun
Zhu, Liguo
Li, Zeren
Classification of Amino Acids Using Hybrid Terahertz Spectrum and an Efficient Channel Attention Convolutional Neural Network
title Classification of Amino Acids Using Hybrid Terahertz Spectrum and an Efficient Channel Attention Convolutional Neural Network
title_full Classification of Amino Acids Using Hybrid Terahertz Spectrum and an Efficient Channel Attention Convolutional Neural Network
title_fullStr Classification of Amino Acids Using Hybrid Terahertz Spectrum and an Efficient Channel Attention Convolutional Neural Network
title_full_unstemmed Classification of Amino Acids Using Hybrid Terahertz Spectrum and an Efficient Channel Attention Convolutional Neural Network
title_short Classification of Amino Acids Using Hybrid Terahertz Spectrum and an Efficient Channel Attention Convolutional Neural Network
title_sort classification of amino acids using hybrid terahertz spectrum and an efficient channel attention convolutional neural network
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9231080/
https://www.ncbi.nlm.nih.gov/pubmed/35745458
http://dx.doi.org/10.3390/nano12122114
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