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Asymmetric Michael Addition in Synthesis of β-Substituted GABA Derivatives

γ-Aminobutyric acid (GABA) represents one of the most prolific structural units widely used in the design of modern pharmaceuticals. For example, β-substituted GABA derivatives are found in numerous neurological drugs, such as baclofen, phenibut, tolibut, pregabalin, phenylpiracetam, brivaracetam, a...

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Detalles Bibliográficos
Autores principales: Han, Jianlin, Escorihuela, Jorge, Fustero, Santos, Landa, Aitor, Soloshonok, Vadim A., Sorochinsky, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9231165/
https://www.ncbi.nlm.nih.gov/pubmed/35744921
http://dx.doi.org/10.3390/molecules27123797