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Pharmacokinetic–Pharmacometabolomic Approach in Early-Phase Clinical Trials: A Way Forward for Targeted Therapy in Type 2 Diabetes
Pharmacometabolomics in early phase clinical trials demonstrate the metabolic profiles of a subject responding to a drug treatment in a controlled environment, whereas pharmacokinetics measure the drug plasma concentration in human circulation. Application of the personalized peak plasma concentrati...
Autores principales: | Tee, Khim Boon, Ibrahim, Luqman, Hashim, Najihah Mohd, Saiman, Mohd Zuwairi, Zakaria, Zaril Harza, Huri, Hasniza Zaman |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9231303/ https://www.ncbi.nlm.nih.gov/pubmed/35745841 http://dx.doi.org/10.3390/pharmaceutics14061268 |
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