Quantitative Analysis of Glassy State Relaxation and Ostwald Ripening during Annealing Using Freeze-Drying Microscopy

Supercooling during the freezing of pharmaceutical solutions often leads to suboptimal freeze-drying results, such as long primary drying times or a collapse in the cake structure. Thermal treatment of the frozen solution, known as annealing, can improve those issues by influencing properties such a...

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Detalles Bibliográficos
Autores principales: Kharatyan, Tigran, Gopireddy, Srikanth R., Ogawa, Toru, Kodama, Tatsuhiro, Nishimoto, Norihiro, Osada, Sayaka, Scherließ, Regina, Urbanetz, Nora A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9231378/
https://www.ncbi.nlm.nih.gov/pubmed/35745749
http://dx.doi.org/10.3390/pharmaceutics14061176

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9231378/
https://www.ncbi.nlm.nih.gov/pubmed/35745749
http://dx.doi.org/10.3390/pharmaceutics14061176

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