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Circadian protection against bacterial skin infection by epidermal CXCL14-mediated innate immunity

The epidermis is the outermost layer of the skin and the body’s primary barrier to external pathogens; however, the early epidermal immune response remains to be mechanistically understood. We show that the chemokine CXCL14, produced by epidermal keratinocytes, exhibits robust circadian fluctuations...

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Detalles Bibliográficos
Autores principales: Tsujihana, Kojiro, Tanegashima, Kosuke, Santo, Yasuko, Yamada, Hiroyuki, Akazawa, Sota, Nakao, Ryuta, Tominaga, Keiko, Saito, Risa, Nishito, Yasumasa, Hata, Ryu-Ichiro, Nakamura, Tomonori, Murai, Iori, Kono, Yuka, Sugawa, Maho, Tanioka, Miki, Egawa, Gyohei, Doi, Masao, Isa, Tadashi, Kabashima, Kenji, Hara, Takahiko, Okamura, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9231475/
https://www.ncbi.nlm.nih.gov/pubmed/35704759
http://dx.doi.org/10.1073/pnas.2116027119