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Circadian protection against bacterial skin infection by epidermal CXCL14-mediated innate immunity
The epidermis is the outermost layer of the skin and the body’s primary barrier to external pathogens; however, the early epidermal immune response remains to be mechanistically understood. We show that the chemokine CXCL14, produced by epidermal keratinocytes, exhibits robust circadian fluctuations...
Autores principales: | Tsujihana, Kojiro, Tanegashima, Kosuke, Santo, Yasuko, Yamada, Hiroyuki, Akazawa, Sota, Nakao, Ryuta, Tominaga, Keiko, Saito, Risa, Nishito, Yasumasa, Hata, Ryu-Ichiro, Nakamura, Tomonori, Murai, Iori, Kono, Yuka, Sugawa, Maho, Tanioka, Miki, Egawa, Gyohei, Doi, Masao, Isa, Tadashi, Kabashima, Kenji, Hara, Takahiko, Okamura, Hitoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9231475/ https://www.ncbi.nlm.nih.gov/pubmed/35704759 http://dx.doi.org/10.1073/pnas.2116027119 |
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