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Raf Kinase Inhibitory Protein regulates the cAMP-dependent protein kinase signaling pathway through a positive feedback loop

Raf Kinase Inhibitory Protein (RKIP) maintains cellular robustness and prevents the progression of diseases such as cancer and heart disease by regulating key kinase cascades including MAP kinase and protein kinase A (PKA). Phosphorylation of RKIP at S153 by Protein Kinase C (PKC) triggers a switch...

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Detalles Bibliográficos
Autores principales:	Lee, Jiyoung, Olivieri, Cristina, Ong, Colin, Masterson, Larry R., Gomes, Suzana, Lee, Bok-Soon, Schaefer, Florian, Lorenz, Kristina, Veglia, Gianluigi, Rosner, Marsha Rich
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2022
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9231499/ https://www.ncbi.nlm.nih.gov/pubmed/35696587 http://dx.doi.org/10.1073/pnas.2121867119

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