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Kinetic model for reversible radical transfer in ribonucleotide reductase

The enzyme ribonucleotide reductase (RNR), which catalyzes the reduction of ribonucleotides to deoxynucleotides, is vital for DNA synthesis, replication, and repair in all living organisms. Its mechanism requires long-range radical translocation over ∼32 Å through two protein subunits and the interv...

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Detalles Bibliográficos
Autores principales:	Reinhardt, Clorice R., Konstantinovsky, Daniel, Soudackov, Alexander V., Hammes-Schiffer, Sharon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2022
Materias:	Physical Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9231603/ https://www.ncbi.nlm.nih.gov/pubmed/35714287 http://dx.doi.org/10.1073/pnas.2202022119

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