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Structural basis for ultrapotent antibody-mediated neutralization of human metapneumovirus

Human metapneumovirus (hMPV) is a leading cause of morbidity and hospitalization among children worldwide, however, no vaccines or therapeutics are currently available for hMPV disease prevention and treatment. The hMPV fusion (F) protein is the sole target of neutralizing antibodies. To map the imm...

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Detalles Bibliográficos
Autores principales: Banerjee, Avik, Huang, Jiachen, Rush, Scott A., Murray, Jackelyn, Gingerich, Aaron D., Royer, Fredejah, Hsieh, Ching-Lin, Tripp, Ralph A., McLellan, Jason S., Mousa, Jarrod J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9231621/
https://www.ncbi.nlm.nih.gov/pubmed/35696580
http://dx.doi.org/10.1073/pnas.2203326119