Functional classification and validation of yeast prenylation motifs using machine learning and genetic reporters

Protein prenylation by farnesyltransferase (FTase) is often described as the targeting of a cysteine-containing motif (CaaX) that is enriched for aliphatic amino acids at the a(1) and a(2) positions, while quite flexible at the X position. Prenylation prediction methods often rely on these features...

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Detalles Bibliográficos
Autores principales: Berger, Brittany M., Yeung, Wayland, Goyal, Arnav, Zhou, Zhongliang, Hildebrandt, Emily R., Kannan, Natarajan, Schmidt, Walter K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9231725/
https://www.ncbi.nlm.nih.gov/pubmed/35749383
http://dx.doi.org/10.1371/journal.pone.0270128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9231725/
https://www.ncbi.nlm.nih.gov/pubmed/35749383
http://dx.doi.org/10.1371/journal.pone.0270128

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