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HIV-1 Nef-mediated downregulation of CD155 results in viral restriction by KIR2DL5(+) NK cells

Antiviral NK cell activity is regulated through the interaction of activating and inhibitory NK cell receptors with their ligands on infected cells. HLA class I molecules serve as ligands for most killer cell immunoglobulin-like receptors (KIRs), but no HLA class I ligands for the inhibitory NK cell...

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Detalles Bibliográficos
Autores principales: Fittje, Pia, Hœlzemer, Angelique, Garcia-Beltran, Wilfredo F., Vollmers, Sarah, Niehrs, Annika, Hagemann, Kerri, Martrus, Glòria, Körner, Christian, Kirchhoff, Frank, Sauter, Daniel, Altfeld, Marcus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9231786/
https://www.ncbi.nlm.nih.gov/pubmed/35749424
http://dx.doi.org/10.1371/journal.ppat.1010572