Translational regulation of TFH cell differentiation and autoimmune pathogenesis

Little is known regarding T cell translational regulation. We demonstrate that T follicular helper (TFH) cells use a previously unknown mechanism of selective messenger RNA (mRNA) translation for their differentiation, role in B cell maturation, and in autoimmune pathogenesis. We show that TFH cells...

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Detalles Bibliográficos
Autores principales: Patel, Preeyam S., Pérez-Baos, Sandra, Walters, Beth, Orlen, Margo, Volkova, Angelina, Ruggles, Kelly, Park, Christopher Y., Schneider, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9232117/
https://www.ncbi.nlm.nih.gov/pubmed/35749506
http://dx.doi.org/10.1126/sciadv.abo1782

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