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Prevalence of depression and associated factors among adult cancer patients receiving chemotherapy during the era of COVID-19 in Ethiopia. Hospital-based cross-sectional study

BACKGROUND: Depression is a major public health problem among cancer patients undergoing chemotherapy. It compromises patient outcomes, resulting in higher rates of mortality. Currently, there are little data on the prevalence of depression in Sub-Sharan countries. Therefore, the current study was d...

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Autores principales: Belete, Abebe Muche, Alemagegn, Anmut, Mulu, Anemut Tilahun, Yazie, Taklo Simeneh, Bewket, Bekalu, Asefa, Adisu, Shiferaw, Wendimeneh Shibabaw
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9232136/
https://www.ncbi.nlm.nih.gov/pubmed/35749489
http://dx.doi.org/10.1371/journal.pone.0270293
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author Belete, Abebe Muche
Alemagegn, Anmut
Mulu, Anemut Tilahun
Yazie, Taklo Simeneh
Bewket, Bekalu
Asefa, Adisu
Shiferaw, Wendimeneh Shibabaw
author_facet Belete, Abebe Muche
Alemagegn, Anmut
Mulu, Anemut Tilahun
Yazie, Taklo Simeneh
Bewket, Bekalu
Asefa, Adisu
Shiferaw, Wendimeneh Shibabaw
author_sort Belete, Abebe Muche
collection PubMed
description BACKGROUND: Depression is a major public health problem among cancer patients undergoing chemotherapy. It compromises patient outcomes, resulting in higher rates of mortality. Currently, there are little data on the prevalence of depression in Sub-Sharan countries. Therefore, the current study was done to assess the prevalence of depression among adult cancer patients and its associated factors in Ethiopia. METHOD: An institutional based cross-sectional study was conducted among 420 adult cancer patients from 1(st) March to April 30, 2021. Systematic random sampling technique was used to recruit participants. Depression was assessed using the Patient Health Questionnaire-9. The collected data were coded and entered into Epi-data version 4.2 and exported to SPSS version 25 for analysis. Bivariate binary logistic regression was performed to select factors that will be included in multivariate analysis, and variables with a p-value < 0.05 were included in multivariate analysis. In multivariate analysis, odds ratios and their 95% confidence intervals were computed and variables with p-value < 0.05 were considered to declare a significant association. RESULTS: In this study, the prevalence of depression was 33.1% (95% CI = 0.2858, 0.3761). Minimal symptoms of depression, minor depression, moderate depression, moderate severe depression, and severe depression were found to be 272 (64.8%), 9 (2.1%), 104 (24.8%), 28 (6.7%), and 7 (1.7%), respectively. Those cancer patients who had unemployed status, sacked from jobs, and had stage IV cancer were most likely to develop depression, whereas patients who completed primary education, colon, prostate and cervical cancer were less likely to have depression. CONCLUSION: Depression is found to be a major public health concern for adult cancer patients in Ethiopia. To reduce the occurrence of depression among cancer patients, special attention is needed.
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spelling pubmed-92321362022-06-25 Prevalence of depression and associated factors among adult cancer patients receiving chemotherapy during the era of COVID-19 in Ethiopia. Hospital-based cross-sectional study Belete, Abebe Muche Alemagegn, Anmut Mulu, Anemut Tilahun Yazie, Taklo Simeneh Bewket, Bekalu Asefa, Adisu Shiferaw, Wendimeneh Shibabaw PLoS One Research Article BACKGROUND: Depression is a major public health problem among cancer patients undergoing chemotherapy. It compromises patient outcomes, resulting in higher rates of mortality. Currently, there are little data on the prevalence of depression in Sub-Sharan countries. Therefore, the current study was done to assess the prevalence of depression among adult cancer patients and its associated factors in Ethiopia. METHOD: An institutional based cross-sectional study was conducted among 420 adult cancer patients from 1(st) March to April 30, 2021. Systematic random sampling technique was used to recruit participants. Depression was assessed using the Patient Health Questionnaire-9. The collected data were coded and entered into Epi-data version 4.2 and exported to SPSS version 25 for analysis. Bivariate binary logistic regression was performed to select factors that will be included in multivariate analysis, and variables with a p-value < 0.05 were included in multivariate analysis. In multivariate analysis, odds ratios and their 95% confidence intervals were computed and variables with p-value < 0.05 were considered to declare a significant association. RESULTS: In this study, the prevalence of depression was 33.1% (95% CI = 0.2858, 0.3761). Minimal symptoms of depression, minor depression, moderate depression, moderate severe depression, and severe depression were found to be 272 (64.8%), 9 (2.1%), 104 (24.8%), 28 (6.7%), and 7 (1.7%), respectively. Those cancer patients who had unemployed status, sacked from jobs, and had stage IV cancer were most likely to develop depression, whereas patients who completed primary education, colon, prostate and cervical cancer were less likely to have depression. CONCLUSION: Depression is found to be a major public health concern for adult cancer patients in Ethiopia. To reduce the occurrence of depression among cancer patients, special attention is needed. Public Library of Science 2022-06-24 /pmc/articles/PMC9232136/ /pubmed/35749489 http://dx.doi.org/10.1371/journal.pone.0270293 Text en © 2022 Belete et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Belete, Abebe Muche
Alemagegn, Anmut
Mulu, Anemut Tilahun
Yazie, Taklo Simeneh
Bewket, Bekalu
Asefa, Adisu
Shiferaw, Wendimeneh Shibabaw
Prevalence of depression and associated factors among adult cancer patients receiving chemotherapy during the era of COVID-19 in Ethiopia. Hospital-based cross-sectional study
title Prevalence of depression and associated factors among adult cancer patients receiving chemotherapy during the era of COVID-19 in Ethiopia. Hospital-based cross-sectional study
title_full Prevalence of depression and associated factors among adult cancer patients receiving chemotherapy during the era of COVID-19 in Ethiopia. Hospital-based cross-sectional study
title_fullStr Prevalence of depression and associated factors among adult cancer patients receiving chemotherapy during the era of COVID-19 in Ethiopia. Hospital-based cross-sectional study
title_full_unstemmed Prevalence of depression and associated factors among adult cancer patients receiving chemotherapy during the era of COVID-19 in Ethiopia. Hospital-based cross-sectional study
title_short Prevalence of depression and associated factors among adult cancer patients receiving chemotherapy during the era of COVID-19 in Ethiopia. Hospital-based cross-sectional study
title_sort prevalence of depression and associated factors among adult cancer patients receiving chemotherapy during the era of covid-19 in ethiopia. hospital-based cross-sectional study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9232136/
https://www.ncbi.nlm.nih.gov/pubmed/35749489
http://dx.doi.org/10.1371/journal.pone.0270293
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