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Long-term persistence of viral RNA and inflammation in the CNS of macaques exposed to aerosolized Venezuelan equine encephalitis virus
Venezuelan equine encephalitis virus (VEEV) is a positively-stranded RNA arbovirus of the genus Alphavirus that causes encephalitis in humans. Cynomolgus macaques are a relevant model of the human disease caused by VEEV and are useful in exploring pathogenic mechanisms and the host response to VEEV...
Autores principales: | Ma, Henry, Albe, Joseph R., Gilliland, Theron, McMillen, Cynthia M., Gardner, Christina L., Boyles, Devin A., Cottle, Emily L., Dunn, Matthew D., Lundy, Jeneveve D., Salama, Noah, O’Malley, Katherine J., Pandrea, Ivona, Teichert, Tobias, Barrick, Stacey, Klimstra, William B., Hartman, Amy L., Reed, Douglas S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9232170/ https://www.ncbi.nlm.nih.gov/pubmed/35696423 http://dx.doi.org/10.1371/journal.ppat.1009946 |
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