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Long-term persistence of viral RNA and inflammation in the CNS of macaques exposed to aerosolized Venezuelan equine encephalitis virus

Venezuelan equine encephalitis virus (VEEV) is a positively-stranded RNA arbovirus of the genus Alphavirus that causes encephalitis in humans. Cynomolgus macaques are a relevant model of the human disease caused by VEEV and are useful in exploring pathogenic mechanisms and the host response to VEEV...

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Detalles Bibliográficos
Autores principales: Ma, Henry, Albe, Joseph R., Gilliland, Theron, McMillen, Cynthia M., Gardner, Christina L., Boyles, Devin A., Cottle, Emily L., Dunn, Matthew D., Lundy, Jeneveve D., Salama, Noah, O’Malley, Katherine J., Pandrea, Ivona, Teichert, Tobias, Barrick, Stacey, Klimstra, William B., Hartman, Amy L., Reed, Douglas S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9232170/
https://www.ncbi.nlm.nih.gov/pubmed/35696423
http://dx.doi.org/10.1371/journal.ppat.1009946

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