Shaoyao-Gancao Decoction Promoted Microglia M2 Polarization via the IL-13-Mediated JAK2/STAT6 Pathway to Alleviate Cerebral Ischemia-Reperfusion Injury

Microglia in the penumbra shifted from M2 to M1 phenotype between 3 and 5 days after cerebral ischemia-reperfusion, which promoted local inflammation and injury. Shaoyao-Gancao Decoction (SGD) has been found to result in a significant upregulation of IL-13 in the penumbra, which has been shown to in...

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Detalles Bibliográficos
Autores principales: Lu, Juanjuan, Wang, Jie, Yu, Long, Cui, Rong, Zhang, Ying, Ding, Hanqing, Yan, Guofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9232306/
https://www.ncbi.nlm.nih.gov/pubmed/35757105
http://dx.doi.org/10.1155/2022/1707122

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9232306/
https://www.ncbi.nlm.nih.gov/pubmed/35757105
http://dx.doi.org/10.1155/2022/1707122

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